Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1993-10-15
1995-03-14
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530324, 530334, 435 691, 930DIG821, A61K 3700, A61K 3702, C07K 710, C12P 2102
Patent
active
053977726
ABSTRACT:
Disclosed are proteins derived from the sand fly Lutzomyia longipalpis capable of inducing vasodilation in mammals, and data characterizing the proteins and nucleic acid encoding the proteins. Also disclosed is a method for temporarily inactivating the immune system in a mammal comprising administering to the mammal the Lutzomyia protein, CGRP, calcitonin, or active immune suppressing analogs thereof.
REFERENCES:
patent: 4839343 (1989-06-01), Waeber et al.
Brain et al. "Calcitonin gene-related peptide is a potent vasodilator" Nature 1985, vol. 313, pp. 54-56.
Papst et al. J. Exp. Med. (1980) 151:101-114.
Amara et al. Nature (1982) 298:240-244.
Johnson et al. J. Immunol. (1983) 131(2):1038-1043.
Adams et al. Ann. Rev. Immunol. (1984) 2:283-318.
Pickett et al. Eur. J. Biochem. (1984) 143:35-38.
Murray et al. J. Immunol. (1985) 3:1619-1622.
Ribeiro et al. 83A Comp. Biochem. Physiol. (1986) 4:683-686.
Buus et al. Immunol. Reviews (1987) 98:115-141.
Unanue et al. Ann. L'Institute Pasteur (1987) 138:489-492.
Zaidi et al. Quart. J. Experimental Physiol. (19,87) 72:371-408.
Stryer et al. Biochem. (1988) Third Edition.
Titus et al. Science (1988) 239:1306-1308.
Tsunawaki et al. Nature (1988) 334:260-262.
Umeda et al. Biochem. Biophys. Research Comm. (1988) 154(1):227-235.
Casini et al. Naunyn-Schmiedeberg's Arch Pharmacol. (1989) 339:354-358.
Ribeiro et al. Science (1989) 243:212-214.
Lerner Ethan A.
Remold Heinz G.
Ribeiro José M. C.
Titus Richard G.
Robinson Douglas W.
The President and Fellows of Harvard College
Weber Jon P.
LandOfFree
Vasodilatory peptides from the salivary gland of the sand fly Lu does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Vasodilatory peptides from the salivary gland of the sand fly Lu, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vasodilatory peptides from the salivary gland of the sand fly Lu will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-713831