Vasodilatory peptides from the salivary gland of the sand fly Lu

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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530324, 530334, 435 691, 930DIG821, A61K 3700, A61K 3702, C07K 710, C12P 2102

Patent

active

053977726

ABSTRACT:
Disclosed are proteins derived from the sand fly Lutzomyia longipalpis capable of inducing vasodilation in mammals, and data characterizing the proteins and nucleic acid encoding the proteins. Also disclosed is a method for temporarily inactivating the immune system in a mammal comprising administering to the mammal the Lutzomyia protein, CGRP, calcitonin, or active immune suppressing analogs thereof.

REFERENCES:
patent: 4839343 (1989-06-01), Waeber et al.
Brain et al. "Calcitonin gene-related peptide is a potent vasodilator" Nature 1985, vol. 313, pp. 54-56.
Papst et al. J. Exp. Med. (1980) 151:101-114.
Amara et al. Nature (1982) 298:240-244.
Johnson et al. J. Immunol. (1983) 131(2):1038-1043.
Adams et al. Ann. Rev. Immunol. (1984) 2:283-318.
Pickett et al. Eur. J. Biochem. (1984) 143:35-38.
Murray et al. J. Immunol. (1985) 3:1619-1622.
Ribeiro et al. 83A Comp. Biochem. Physiol. (1986) 4:683-686.
Buus et al. Immunol. Reviews (1987) 98:115-141.
Unanue et al. Ann. L'Institute Pasteur (1987) 138:489-492.
Zaidi et al. Quart. J. Experimental Physiol. (19,87) 72:371-408.
Stryer et al. Biochem. (1988) Third Edition.
Titus et al. Science (1988) 239:1306-1308.
Tsunawaki et al. Nature (1988) 334:260-262.
Umeda et al. Biochem. Biophys. Research Comm. (1988) 154(1):227-235.
Casini et al. Naunyn-Schmiedeberg's Arch Pharmacol. (1989) 339:354-358.
Ribeiro et al. Science (1989) 243:212-214.

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