Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-05-26
1989-05-30
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544380, A61K 31645
Patent
active
048351563
ABSTRACT:
A dihydrodibenzocycloheptyliden-ethyl-piperazine derivative of the general formula: ##STR1## in which, R=--CH.dbd.CH.sub.2 ; --CH.sub.2 OH; --COOH; --CO.sub.2 C.sub.2 H.sub.5 ; --CH.dbd.CH--CO.sub.2 CH.sub.3 ; --CH.dbd.CH--CO.sub.2 CH.sub.3, --C.sub.6 H.sub.5, ##STR2## or pharmaceutically acceptable salts thereof, are disclosed. The compounds of the invention are useful in pharmaceutical compositions for the treatment of pathologies responsive to vasodilatory agents.
REFERENCES:
patent: 3906110 (1975-09-01), Francis
patent: 4381305 (1983-04-01), Casagrande
Chemical Abstracts 93: 197538f (1980).
Chemical Abstracts 84: 164397v (1976).
Plilai, Agents Acting on the Central Nervous System: part XXVI; Indian J. Chem. vol. 14B, Sep. 1976; pp. 714-716.
Chemical Abstracts 81: 120194k (1974).
Andreoli Romeo R.
Bruseghini Leonida
Cirera Xavier D.
Irrure Jose P.
Lloveras Pedro P.
Ivy C. Warren
Sociedad Espanola De Especialidades Terepeuticas, S.A.
Striker Michael J.
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