Vasodilators and .beta.-adrenoceptor antagonists

Details Vasodilators and .beta.-adrenoceptor antagonists Vasodilators and .beta.-adrenoceptor antagonists

1985-05-16

1987-03-24

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540362, 544238, 544239, 548215, 549517, 549560, 560 39, 560 42, 564425, 564443, 568627, 568648, 568650, 568654, 514913, 514929, A61K 3150, C07D23704, C07D20508, C07D41312

Patent

active

046525637

ABSTRACT:
This invention relates to dihydropyridazinone compounds having a cyclopropylmethoxyethyl group in the 6-substituent. These compounds are vasodilators and .beta.-adrenoceptor antagonists. A particular compound of the invention is 6-[4-[3-[2-hydroxy-3-[4-(2-(cyclopropylmethoxy) ethyl)phenoxy]propylamino]propionamido]phenyl]-5-methyl-4,5-dihydro-3 (2H)-pyridazinone.

REFERENCES:
patent: 3746712 (1973-07-01), Ross et al.
patent: 4252984 (1981-02-01), Manoury et al.
patent: 4397854 (1983-08-01), Sircar
Derwent Abstract 83-785473 (J5 8146-570-A).
Curran et al., J. Med. Chem. 17:273-281 (1974).

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