Vasodilating 1,1-di-(2-methoxycarbonyl-ethyl)-1,2,3,4,5,6,12,12b

Details Vasodilating 1,1-di-(2-methoxycarbonyl-ethyl)-1,2,3,4,5,6,12,12b Vasodilating 1,1-di-(2-methoxycarbonyl-ethyl)-1,2,3,4,5,6,12,12b

1977-12-29

1979-11-06

Ford, John M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546 70, C07D47104, A61K 31445

Patent

active

041736427

ABSTRACT:
New pharmacologically active octahydro-indolo[2,3-a]quinolizine derivatives of the formula ##STR1## wherein Q is hydrogen or an A--CH.sub.2 --CH.sub.2 -- group and A is cyano or -COOR, wherein R is C.sub.1-6 alkyl are prepared by reacting 2,3,4,6,7,12-hexahydro-indolo[2,3-a]quinolizine with a compound of the formula CH.sub.2 .dbd.CH--A, and reducing the obtained hexahydroindolo[2,3-a] quinolizine derivative of the formula ##STR2##

REFERENCES:
patent: 3536725 (1970-10-01), Schvt
patent: 3830823 (1974-08-01), Castaigne
patent: 4033969 (1977-07-01), Sevenet et al.
patent: 4057551 (1977-11-01), Szantay et al.
patent: 4057551 (1977-11-01), Szantay et al.
patent: 4089856 (1978-05-01), Szantay et al.
Chemical Abstracts: 85:46624q, (1976) [Szantay et al., German Offen. 2,541,484, 4/15/76].
Imbert; T. et al., Bull. Soc. Chim. France, 1973 (No. 9-10), 2705-2709.

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