Vascular prosthesis and method of making the same

Details Vascular prosthesis and method of making the same Vascular prosthesis and method of making the same

1979-05-23

1981-09-01

Marantz, Sidney

Coating processes

Electrical product produced

Integrated circuit, printed circuit, or circuit board

3 1, 427 2, A61F 124

Patent

active

042863414

ABSTRACT:
A vascular prosthesis and its method of fabrication. The prosthesis takes the form of a flexible and conformable support tube having a luminal surface formed of a smooth, homogenous, and substantially non-thrombogenic hydrogel having relatively small pores or microvoids suitable for tissue ingrowth but resistant to thrombus formation, and having an outer surface formed of essentially the same hydrogel having a heterogenous microstructure which includes relatively large pores or macrovoids especially suitable for cellular ingrowth from perigraft sources and attachment sites. In one embodiment, the tubular substrate is foraminous and the inner and outer hydrogel layers merge through the interstices of the substrate to provide a unified ground substance characterized by strata having selectively different pore characteristics for promoting effective endothelialization and for reducing possibilities of thrombotic occlusion.

REFERENCES:
patent: 3632416 (1972-01-01), Shepherd
patent: 3663288 (1972-05-01), Miller
patent: 4042978 (1977-08-01), Jones
patent: 4074039 (1978-02-01), Lim
patent: 4193138 (1980-03-01), Okita

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