Vascular implant device

Details Vascular implant device Vascular implant device

2005-04-11

2010-06-29

Hartley, Michael G (Department: 1618)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

Reexamination Certificate

active

07744914

ABSTRACT:
Vascular smooth muscle cells (VSMCs) adhere to and orient along micropatterned grooves having a depth of 1 to 10 μm and a width of 1 to 20 μm that are imposed on the surface of a vascular implant device. The VSMCs maintain an elongated morphology and reduced proliferation resulting in a decrease in occurrence of intimal hyperplasia upon device implantation.

REFERENCES:
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patent: 2004/0220660 (2004-11-01), Shanley et al.
patent: 2005/0209684 (2005-09-01), Alexander et al.
patent: 2006/0088571 (2006-04-01), Chen et al.
patent: 2007/0141100 (2007-06-01), Sung et al.
patent: WO 03045582 (2003-05-01), None
Cordis Endovascular Product Information Sheet, 1999.

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