Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Having plural layers
Reexamination Certificate
2007-05-01
2007-05-01
Gherbi, Suzette (Department: 3738)
Prosthesis (i.e., artificial body members), parts thereof, or ai
Arterial prosthesis
Having plural layers
C428S036900, C623S001460
Reexamination Certificate
active
10763493
ABSTRACT:
One aspect of the invention relates to a graft, a surface of which is coated with an amphiphilic block copolymer that includes both hydrophobic and hydrophilic polymer chains. An amphiphilic block copolymer coating according to the invention can serve as a carrier for a very broad range of drugs, possibly including every drug presently used, being considered for use, or likely to be used in the future to inhibit stenosis. The release rates of the drugs can be controlled, for example, through the length of the polymer chains, through their ratio, or through the degree of cross-linking.
REFERENCES:
patent: 4733665 (1988-03-01), Palmaz
patent: 4776337 (1988-10-01), Palmaz
patent: 4888389 (1989-12-01), Kennedy et al.
patent: 4942204 (1990-07-01), Kennedy
patent: 5024671 (1991-06-01), Tu et al.
patent: 5037392 (1991-08-01), Hillstead
patent: 5051272 (1991-09-01), Hermes et al.
patent: 5073381 (1991-12-01), Ivan et al.
patent: 5108424 (1992-04-01), Hoffman, Jr. et al.
patent: 5116318 (1992-05-01), Hillstead
patent: 5180366 (1993-01-01), Woods
patent: 5185408 (1993-02-01), Tang et al.
patent: 5197977 (1993-03-01), Hoffman, Jr. et al.
patent: 5246451 (1993-09-01), Trescony et al.
patent: 5246452 (1993-09-01), Sinnott
patent: 5283257 (1994-02-01), Gregory et al.
patent: 5304121 (1994-04-01), Sahatjian
patent: 5370681 (1994-12-01), Herweck
patent: 5383925 (1995-01-01), Schmitt
patent: 5383927 (1995-01-01), De Goicoechea et al.
patent: 5383928 (1995-01-01), Scott et al.
patent: 5417981 (1995-05-01), Endo
patent: 5449382 (1995-09-01), Dayton
patent: 5464650 (1995-11-01), Berg et al.
patent: 5500013 (1996-03-01), Buscemi et al.
patent: 5516781 (1996-05-01), Morris et al.
patent: 5545208 (1996-08-01), Wolff et al.
patent: 5563146 (1996-10-01), Morris et al.
patent: 5578075 (1996-11-01), Dayton
patent: 5605696 (1997-02-01), Eury et al.
patent: 5609629 (1997-03-01), Fearnot
patent: 5624411 (1997-04-01), Tuch
patent: 5665728 (1997-09-01), Morris et al.
patent: 5679400 (1997-10-01), Tuch
patent: 5716981 (1998-02-01), Hunter et al.
patent: 5733925 (1998-03-01), Kunz et al.
patent: 5772864 (1998-06-01), M.o slashed.ller et al.
patent: 5807944 (1998-09-01), Hirt et al.
patent: 5811447 (1998-09-01), Kunz et al.
patent: 5824049 (1998-10-01), Ragheb
patent: 5873904 (1999-02-01), Ragheb
patent: 5962620 (1999-10-01), Reich et al.
patent: 5981568 (1999-11-01), Kunz et al.
patent: 5993972 (1999-11-01), Reich et al.
patent: 6074659 (2000-06-01), Kunz et al.
patent: 6096070 (2000-08-01), Ragheb
patent: 6120536 (2000-09-01), Ding et al.
patent: 6120847 (2000-09-01), Yang et al.
patent: 6156062 (2000-12-01), McGuinness
patent: 6156373 (2000-12-01), Zhong
patent: 6162247 (2000-12-01), Weadock et al.
patent: 6171609 (2001-01-01), Kunz
patent: 6200589 (2001-03-01), Kennedy et al.
patent: 6200960 (2001-03-01), Khachigian
patent: 6206916 (2001-03-01), Furst
patent: 6221099 (2001-04-01), Andersen et al.
patent: 6245537 (2001-06-01), Williams
patent: 6258121 (2001-07-01), Yang et al.
patent: 6268390 (2001-07-01), Kunz
patent: 6273913 (2001-08-01), Wright et al.
patent: 6287628 (2001-09-01), Hossainey et al.
patent: 6299604 (2001-10-01), Ragheb
patent: 6306421 (2001-10-01), Kunz et al.
patent: 6322847 (2001-11-01), Zhong
patent: 6333347 (2001-12-01), Hunter et al.
patent: 6356600 (2002-03-01), Kirsteins
patent: 6358989 (2002-03-01), Kunz
patent: 6365171 (2002-04-01), Kennedy et al.
patent: 6368658 (2002-04-01), Schwarz
patent: 6369065 (2002-04-01), Chatelain
patent: 6379379 (2002-04-01), Wang
patent: 6379381 (2002-04-01), Hossainey et al.
patent: 6391052 (2002-05-01), Buirge et al.
patent: 6436133 (2002-08-01), Furst et al.
patent: 6491938 (2002-12-01), Kunz et al.
patent: 6515009 (2003-02-01), Kunz et al.
patent: 6517571 (2003-02-01), Brauker et al.
patent: 6528584 (2003-03-01), Kennedy et al.
patent: 6530951 (2003-03-01), Bates
patent: 6545097 (2003-04-01), Pinchuk et al.
patent: 6555157 (2003-04-01), Hossainey et al.
patent: 6555619 (2003-04-01), Kennedy et al.
patent: 6569195 (2003-05-01), Yang et al.
patent: 6569441 (2003-05-01), Kunz
patent: 6583251 (2003-06-01), Chaikof et al.
patent: 6585764 (2003-07-01), Wright et al.
patent: 6599275 (2003-07-01), Fischer
patent: 6599928 (2003-07-01), Kunz et al.
patent: 6607598 (2003-08-01), Schwarz
patent: 6623521 (2003-09-01), Steinke
patent: 6624138 (2003-09-01), Sung
patent: 6641611 (2003-11-01), Jayaraman
patent: 6652575 (2003-11-01), Wang
patent: 6656506 (2003-12-01), Wu
patent: 6656966 (2003-12-01), Garvey
patent: 6663881 (2003-12-01), Kunz et al.
patent: 6695833 (2004-02-01), Frantzen
patent: 6720350 (2004-04-01), Kunz
patent: 6723814 (2004-04-01), Meier et al.
patent: 6726923 (2004-04-01), Iyer et al.
patent: 6730064 (2004-05-01), Ragheb
patent: 6730349 (2004-05-01), Schwarz
patent: 6734194 (2004-05-01), End
patent: 6743805 (2004-06-01), End
patent: 6753071 (2004-06-01), Pacetti
patent: 6759431 (2004-07-01), Hunter
patent: 6770729 (2004-08-01), Van Antwerp
patent: 6774278 (2004-08-01), Ragheb et al.
patent: 6780849 (2004-08-01), Herrmann
patent: 6783793 (2004-08-01), Hossainy
patent: 6808536 (2004-10-01), Wright
patent: 6852353 (2005-02-01), Qiu et al.
patent: 7160592 (2007-01-01), Rypacek et al.
patent: 2002/0032414 (2002-03-01), Ragheb
patent: 2002/0107330 (2002-08-01), Pinchuk et al.
patent: 2003/0026840 (2003-02-01), Plank et al.
patent: 2003/0028243 (2003-02-01), Bates
patent: 2003/0028244 (2003-02-01), Bates
patent: 2003/0036794 (2003-02-01), Ragheb
patent: 2003/0040790 (2003-02-01), Furst
patent: 2003/0064098 (2003-04-01), Kararli et al.
patent: 2003/0083646 (2003-05-01), Sirhan et al.
patent: 2003/0093141 (2003-05-01), Dimatteo et al.
patent: 2003/0099712 (2003-05-01), Jayaraman
patent: 2003/0158598 (2003-08-01), Ashton et al.
patent: 2003/0199969 (2003-10-01), Steinke et al.
patent: 2003/0216534 (2003-11-01), Chaikof et al.
patent: 2003/0228364 (2003-12-01), Nathan
patent: 2003/0229390 (2003-12-01), Ashton et al.
patent: 2003/0229392 (2003-12-01), Wong
patent: 2003/0229393 (2003-12-01), Kutryk et al.
patent: 2004/0047909 (2004-03-01), Ragheb
patent: 2004/0093076 (2004-05-01), White
patent: 2004/0093077 (2004-05-01), White
patent: 2004/0219223 (2004-11-01), Kunz
patent: 2004/0243225 (2004-12-01), Ragheb
patent: WO 99/18998 (1999-04-01), None
Abstract ofPharmacological Properties of Trapidil: Comparison with Other Coronary Vasodilators, Ohnishi H, Kosuzume H, Yamaguchi K, Sato M, Umehara S, Funato H, Itoh C, Suzuki K, Kitamura Y, Suzuki Y, Itoh R., Nippon Yakurigaku Zasshi. Sep. 1980;76(6):495-503.
Abstract ofEffects of Trapidil on Thromboxane A2-induced Aggregation of Platelets, Ischemic Changes in Heart and Biosynthesis of Thromboxane A2, Ohnishi H, Kosuzume H, Hayashi Y, Yamaguchi K, Suzuki Y, Itoh R., Prostaglandins Med. Mar. 1981;6(3):269-81.
Abstract ofAntithromobitic Activity and the Mechanism of Action of Trapidil(Rocornal), Suzuki Y, Yamaguchi K, Shimada S, Kitamura Y, Ohnishi H., Prostaglandins Leukot Med. Dec. 1982;9(6):685-95.
Abstract ofSuppression of Fibroblast Proliferation In Vitro and of Myointimal Hyperplasia In Vivo by the Triazolopyrimidine, Trapidil, Tiell ML, Sussman II, Gordon PB, Saunders RN, Artery. 1983;12(1):33-50.
Influence of Cardiovascular Drugs on Platelet Aggregation, Forster W, Block HU, Giessler C, Heinroth I, Mentz P, Ponicke K, Rettkowski W, Zehl U., : Adv Myocardiol. 1983;4:539-47.
Abstract ofTrapidil in Preventing Restenosis After Balloon Angioplasty in the Ather Osclerotic Rabbit, MW Liu, GS Roubin, KA Robinson, AJ Black, JA Hearn, RJ Siegel, and SB King, 3d Circulation 1990 81: 1089-1093.
Abstract ofEffects of Trapidil(Triazolopyrimidine),a Platelet-Derived Growth Factor Antagonist, in Preventing Restenosis After Percutaneous Transluminal Coronary Angioplasty, Okamoto S, Inden M, Setsuda M, Konishi T, Nakano T, Am Heart J. Jun. 1992;123(6):1439-44.
Abstract ofTrapidil(triazolopyrimidine),A Platelet-Derived Growth Factor Antagonist, Reduces Restenosis After Percutaneous Transluminal Coronary Angioplasty. Results of the Randomized, Double-Blind STARC Study. Studio Trapidil Versus Aspirin Nella Restenosi Coronarica, A M
Brodbeck William
Furst Joseph G.
Fay Sharpe LLP
Gherbi Suzette
ICON Medical Corp.
Turung Brian E.
LandOfFree
Vascular grafts with amphiphilic block copolymer coatings does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Vascular grafts with amphiphilic block copolymer coatings, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vascular grafts with amphiphilic block copolymer coatings will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3753638