Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-02-20
2007-02-20
Spector, Lorraine (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S399000, C514S002600
Reexamination Certificate
active
10924025
ABSTRACT:
There is provided a novel vascular endothelial growth factor, herein designated VEGF-X, in addition to the nucleic acid molecule encoding it, a host cell transformed with said vector and compounds which inhibit or enhance angiogenesis. Also provided is the sequence of a CUB domain present in the sequence of VEGF-X which domain itself prevents angiogenesis and which is used to treat diseases associated with inappropriate vascularisation or angiogenesis.
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Dhanaraj Sridevi N.
Dijkmans Josiena J. H.
Gordon Robert D.
Gosiewska Anna
Sprengel Jörg J.
Janssen Pharmaceutica.N.V.
Shafer Shulamith H
Spector Lorraine
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