Vascular endothelial growth factor 2

Details Vascular endothelial growth factor 2 Vascular endothelial growth factor 2

1998-03-13

2000-03-21

Ulm, John

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 71, 435325, 435243, 4353201, 536 2351, 530399, C12N 1518, C12N 1563, C12N 121, C12N 500

Patent

active

060401575

ABSTRACT:
Disclosed are human VEGF2 polypeptides, biologically active, diagnostically or therapeuticall sefl fragments, analogs, or derivatives thereof, and DNA (RNA) enco such VEGF2 polypeptides. Also provided are procedures for producing such polypeptides by recombinant techniques and antibodies and antagonists against such polypeptides. Such polypeptides may be used therapeutically for stimulating wound healing and for vascular tissue repair. Also provided are methods of using the antibodies and antagonists to inhibit tumor angiogenesis and thus tumor growth, inflammation, diabetic retinopathy, rheumatoid arthritis, and psoriasis.

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