Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-08-31
1998-03-10
Walsh, Stephen
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530350, 530399, A61K 3818, C07K 14475
Patent
active
057261520
ABSTRACT:
Vascular endothelial cell growth factor II is purified from the culture media used to maintain mammalian glioma cells. The protein is a heterodimer, stimulates mitogenesis of mammalian vascular endothelial cells and is useful for the promotion of vascular development and repair. This unique growth factor is also useful in the promotion of tissue repair.
REFERENCES:
patent: 5194596 (1993-03-01), Tischer et al.
patent: 5219739 (1993-06-01), Tischer et al.
patent: 5338840 (1994-08-01), Bayne et al.
Joukov et al. EMBO J. (1996) 15, 290-298.
Conn, et al., Proc. Natl. Acad. Sci. U.S.A, 87: 2628-2632, 1990.
Ferrara & Henzel, Biochem. Biophys. Res. Comm., 161: 851-858, 1989.
Laemmli, Nature, 227: 680-684, 1970.
Saiki et al., Science, 230: 1350-1354, 1985.
Gospodarowicz et al., Proc. Natl. Acad. Sci. U.S.A., 86: 7311-7 15, 1989.
Frohman, et al., Proc. Natl. Acad. Sci. U.S.A., 85: 8998-9002, 1988.
Tischer et al. Biochem & Biophysical Research Comm. 165: 1198, 1989.
Leung et al., Science 246: 1306-1309, 1989.
Conn et al., Proc. Natl. Acad. Sci. U.S.A. 87: 1323-1327, 1990.
Keck et al., Science 246: 1309-1312, 1989.
Bowie et al., Science 247: 1306-1310, 1989.
Conn. Endothelial Cell Growth Factors, Yeshiva University, 1987 pp. 1-162, Ph.D. dissertation.
Bayne Marvin L.
Conn Gregory L.
Thomas, Jr. Kenneth A.
Brown Karen E.
Hand J. Mark
Merck & Co. , Inc.
Tribble Jack L.
Walsh Stephen
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