Varicella-zoster virus vaccine and preparation thereof

Drug – bio-affecting and body treating compositions – Lymphokine

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195 14, 195 18, A61K 3912

Patent

active

040083179

ABSTRACT:
Non-pathogenic varicella-zoster virus mutants are obtained by induction and isolation of temperature-sensitive mutant strains. N-methyl-N'-nitro-N-nitrosoguanidine is employed as mutagenic agent. The obtained mutants are useful for vaccine production.

REFERENCES:
ledinko et al., --Chem. Abst., vol. 80, (1974), p. 56297w.
Casto et al.,--Chem. Abst., vol. 81, (1974), p. 22072z.

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