Variants of RANKL protein

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C435S069100, C435S320100, C435S325000, C514S012200, C536S023500

Reexamination Certificate

active

07399829

ABSTRACT:
The present invention relates to novel, soluble, recombinant variants RANKL (Receptor Activator of Nuclear Factor—κB Ligand) proteins, which may be expressed solubly inE. coli,variants that act as RANKL antagonists, and methods for generating the same.

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