Variants of beta-glucosidase

Details Variants of beta-glucosidase Variants of beta-glucosidase

2008-06-26

2009-12-29

Ramirez, Delia M (Department: 1652)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S252300, C435S252330, C435S069100, C435S209000, C435S325000, C435S320100

Reexamination Certificate

active

07638616

ABSTRACT:
The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.

REFERENCES:
patent: 0126586 (2001-05-01), None
Kawaguchi et al., Cloning and sequencing of the cDNA encoding Beta-glucosidase 1 fromAspergillus aculeatus, Gene, 1996, v. 173, pp. 287-288.
Iwashita et al., The bglA gene ofAspergillus kawachiiencodes both extracellular and cell wall-bound Beta-glucosidases, Applied and Environmental Microbiology, Dec. 1999, pp. 5546-5553.

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