Variant of LAV viruses

Details Variant of LAV viruses Variant of LAV viruses

1991-02-19

1999-02-09

Smith, Lynette F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

530350, 530395, 530324, 4352351, C07H 2102, C07H 2104, C07K 100, C07K 1400

Patent

active

058696318

ABSTRACT:
A variant of a LAV virus, designated LAV.sub.ELI and capable of causing. AIDS. The cDNA and antigens of the LAV.sub.ELI virus can be used for the diagnosis of AIDS and pre-AIDS.

REFERENCES:
U.S. Patent Application Serial No. 7/038,033, filed Apr. 13, 1987, for A Variant of LAV Viruses, Inventors: Marc Alizon et al.
"Radioimmunoassay And Enzyme-Linked Immunoassay of Antibodies Directed Against Lymphadenopathy-Associated Virus (LAV) Proteins Larger Than The Core Protein (P24)", Neurath et al., Journal of Virological Methods, 12, 85-92 (1985).
"Nucleotide Sequence of the AIDS Virus, LAV", Wain-Hobson et al., Cell 40, 9-17 (1985).
"Genomic Diversity of Human T-Lymphotropic Virus Type III (HTLV-III)", Wong-Staal et al., Science, 229, 759-762 (1985).
"Isolation of Human T-Lymphotropic Retrovirus (LAV) from Zairian Married Couple, One With AIDS, One With Prodromes", Ellrodt et al., The Lancet, 1383-1385 (1984).
Complete Nucleotide Sequence of the AIDS Virus, HTLV-III, Ratner et al., Nature, 323, 277-284 (1985).
"Nucleotide Sequence and Expression of An AIDS-Associated Retrovirus (ARV-2)", Sanchez-Pescador et al., Science, 227, 484-492 (1985).
"Nucleic Acid Structure and Expression of the Human AIDS/lymphadenopathy Retrovirus", Muesing et al., Nature, 313 (1985).
Alizon, et al., 1984 "Molecular cloning of lymphadenopathy associated virus" Nature 312: 757-760.
Wain-Hobson, et al., 1985 "Nucleotide sequence of the AIDS Virus, LAV", Cell vol. 40: 9-17.

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