Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Lyase
Reexamination Certificate
2005-03-16
2008-10-07
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Lyase
C435S121000, C435S252300, C435S069100, C435S471000, C435S193000, C536S023200
Reexamination Certificate
active
07432100
ABSTRACT:
The present invention relates to variant aldolase enzymes that are modified so as to produce IHOG (4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid: IHOG), a process for producing an optically active IHOG using the same, and a process for producing an optically active monatin.
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Xu et al., A practical method for interpretatio of threading scores: An application of neural network. Statstica Sinica, 2002, vol. 12: 159-177.
Whisstock et al., Prediction of protein function from protein sequence and strucuture. Q. Rev. Biophys., 2003, vol. 36(3): 307-340.
U.S. Appl. No. 11/146,093, filed Jun. 7, 2005, Sugiyama, et al.
U.S. Appl. No. 11/080,628, filed Mar. 16, 2005, Sugiyama, et al.
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Kashiwagi Tatsuki
Mori Ken-ichi
Sugiyama Masakazu
Suzuki Ei-ichiro
Ajinomoto Co. Inc.
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
Prouty Rebecca E.
Raghu Ganapathirama
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