Variably crosslinked tissue

Details Variably crosslinked tissue Variably crosslinked tissue

2011-04-05

2011-04-05

Kopec, Mark (Department: 1796)

Bleaching and dyeing; fluid treatment and chemical modification

Treatment of hides, skins, feathers and animal tissues

Internal tissues

C623S002100, C623S915000, C623S918000, C623S919000

Reexamination Certificate

active

07918899

ABSTRACT:
Non-glutaraldehyde fixation of an organ or a prosthesis for implantation in a mammal is based upon carbodiimide treatment. A solution containing a sterilizing agent, such as EDC, in combination with a coupling enhancer, such as Sulfo-NHS, and a high concentration of a diamine cross linking agent is used. As a result, only minimal surface reduction occurs during fixation, and the resultant products show a dramatic increase in resistance to calcification.

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