Variable-motion optical tomography of small objects

Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation

Reexamination Certificate

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C382S131000, C382S132000, C600S473000, C600S476000, C356S432000

Reexamination Certificate

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10126026

ABSTRACT:
Motion of an object of interest, such as a cell, has a variable velocity that can be varied on a cell-by-cell basis. Cell velocity is controlled in one example by packing cells into a capillary tube, or any other linear substrate that provides optically equivalent 360 degree viewing access, so that the cells are stationary within the capillary tube, but the capillary tube is translated and rotated mechanically through a variable motion optical tomography reconstruction cylinder. The capillary tube motion may advantageously be controlled in a start-and-stop fashion and translated and rotated at any velocity for any motion interval, under the control of a computer program. As such, there are several configurations of the optical tomography system that take advantage of this controlled motion capability. Additionally, the use of polarization filters and phase plates to reduce light scatter and diffraction background noise is described.

REFERENCES:
patent: 3470373 (1969-09-01), Brewer
patent: 3497690 (1970-02-01), Wheeless, Jr.
patent: 3598471 (1971-08-01), Baldwin
patent: 3657537 (1972-04-01), Wheeless, Jr.
patent: 3748468 (1973-07-01), Hartman
patent: 3833762 (1974-09-01), Gudmundsen
patent: 3960449 (1976-06-01), Carlton
patent: 3999047 (1976-12-01), Green
patent: 4175860 (1979-11-01), Bacus
patent: 4183623 (1980-01-01), Haines
patent: 4200353 (1980-04-01), Hoffman
patent: 4293221 (1981-10-01), Kay
patent: 4657676 (1987-04-01), Keary
patent: 4858128 (1989-08-01), Nowak
patent: 4891829 (1990-01-01), Deckman
patent: 4966576 (1990-10-01), Schulz
patent: 5141609 (1992-08-01), Sweedler et al.
patent: 5308990 (1994-05-01), Takahashi et al.
patent: 5312535 (1994-05-01), Waska et al.
patent: 5321501 (1994-06-01), Swanson et al.
patent: 5402460 (1995-03-01), Johnson
patent: 5630938 (1997-05-01), Feller
patent: 5668887 (1997-09-01), Parker et al.
patent: 5676631 (1997-10-01), Kunz
patent: 5680484 (1997-10-01), Ohyama et al.
patent: 5710429 (1998-01-01), Alfano et al.
patent: 5741411 (1998-04-01), Yeung et al.
patent: 5760901 (1998-06-01), Hill
patent: 5760951 (1998-06-01), Dixon et al.
patent: 5828408 (1998-10-01), Mottin et al.
patent: 5848123 (1998-12-01), Strommer
patent: 5880838 (1999-03-01), Marx et al.
patent: 5915048 (1999-06-01), Hill et al.
patent: 5987158 (1999-11-01), Meyer
patent: 6005617 (1999-12-01), Shimamoto et al.
patent: 6026174 (2000-02-01), Palcic
patent: 6038067 (2000-03-01), George
patent: 6072624 (2000-06-01), Dixon et al.
patent: 6091983 (2000-07-01), Alfano et al.
patent: 6165734 (2000-12-01), Garini
patent: 6201628 (2001-03-01), Basiji
patent: 6211955 (2001-04-01), Basiji
patent: 6215587 (2001-04-01), Alfano et al.
patent: 6248988 (2001-06-01), Krantz
patent: 6249341 (2001-06-01), Basiji et al.
patent: 6251586 (2001-06-01), Mulshine
patent: 6251615 (2001-06-01), Oberhardt
patent: 6252979 (2001-06-01), Lee
patent: 6312914 (2001-11-01), Kardos et al.
patent: 6330106 (2001-12-01), Greenwald et al.
patent: 6388809 (2002-05-01), MacAulay
patent: 6452179 (2002-09-01), Coates et al.
patent: 6529614 (2003-03-01), Chao et al.
patent: 6591003 (2003-07-01), Chu et al.
patent: 2001/0012069 (2001-08-01), Derndinger et al.
patent: 2002/0045525 (2002-04-01), Marziali
patent: 2002/0161534 (2002-10-01), Adler et al.
patent: 2002/0173034 (2002-11-01), Barbera-Guillem
patent: WO 02/095476 (2002-11-01), None
Schmitz, “Perfomance Characteristics of a Silicon Photodiode (SiPD) Based Instrucment for Fast Functional Optical Tomography,” undated, SUNY Downstate Medicial Center Brooklyn, NY.
Schmitz, “Instrumentation for Real-Time Dynamic Optical Tomography,” undated, SUNY Downstate Medicial Center Brooklyn, NY.
Ong, SH, Development of an imaging flow cytometer. Anal Quant Cytol Histol 9(5)pp. 375-382, 1987.
Farichild Imaging, Preliminary Data Sheet CCD525, TDI, Time Delay and Integration Sensor, Jan. 12, 2001.
Farichild Imaging, Preliminary Data Sheet CCD582, TDI, Time Delay and Integration Sensor, Jan. 18, 2000.
Shapiro, HM,Practical Flow Cytometry, 3rded., Wiley-Liss, 1995.
HJ Tiziani and MI Uhde, Three-dimensional analysis by a microlens array confocal arrangements (Applied Optics33, 567 [1994]).
Bayat, S, Le Duc, G, Porra, L, Berrruyer, G, Nemoz, C, Monfraix, S, Fiedler, S, Thomlinson, W, Suortti, P, Standertskjold-Nordenstam, CG, and Sovijarvi, ARA, “Quantitative Functional Lung Imaging with Synchrotron Radiation Using Inhaled Xenon as Contrast Agent”, Physics in Medicine and Biology 46(3287-99) 2001.
Bentley, MD, Ortiz, MC, Ritman, EL, and Romero, JC, “The Use of Microcomputed Tomography to Study Microvasculature in Small Rodents”, American Journal of Physiology (Regulatory Integrative Comp Physiol) 282(R1267-R1279) 2002.
Cheng, PC, Lin, TH, Wang, G, Shinozaki, DM, Kim, HG, and Newberry, SP, “Review on the Development of Cone-beam X-ray Microtomography”, Proceedings of the X-ray Optics and Microanalysis 1992, Institute of Physics Ser. No. 130, Kenway, PB, et al. (eds.), Manchester, UK, Aug. 31-Sep. 4, 1992, pp. 559-566.
Defrise, M, Clack, R, and Townsend, DW, “Image Reconstruction from Truncated, Two-dimensional, Parallel Projections”, Inverse Problems 11(287-313) 1995.
Defrise, M, Noo, F, and Kudo, H, “A Solution to the Long-object Problem in Helical Cone-beam Tomography”, Physics in Medicine and Biology 45(623-43) 2000.
Endo, M, Tsunoo, T, Nakamori, N, and Yoshida, K, “Effect of Scattered Radiation on Image Noise in Cone Beam CT”, Medical Physics 28(4) (469-74) 2001.
Jorgensen, SM, Demirkaya, O, and Ritman, EL, “Three Dimensional Imaging of Vasculature and Parenchyma in Intact Rodent Organs with X-ray Micro-CT”, Am. J. Physiology 275(Heart Circ. Physiol. 44) pp. H1103-H1114, 1998.
Kinney, JH, Johnson, QC, Saroyan, RA, Nichols, MC, Bonse, U, Nusshardt, R, and Pahl, R, “Energy-modulated X-ray Microtomography”, Rev. Sci. Instrum. 59(1)pp. 196-197, 1988.
Kinney, JH and Nichols, MC, “X-ray Tomographic Microscopy (XTM) Using Synchrotron Ratiation”, Annu. Rev. Mater. Sci. 22pp. 121-152, 1992.
Taguchi, K and Aradate, H, “Algorithm for Image Reconstruction in Multi-slice Helical CT”, Medical Physics 25(4) pp. 550-561, 1998.
Yu, DF, Fessler, JA, and Ficaro, EP, “Maximum-Likelihood Transmission Image Reconstruction for Overlapping Transmission Beams”, IEEE Transactions on Medical Imaging 19(11)pp. 1094-1105, 2000.
Sharpe, J, Ahlgren, U et al., “Optical Projection Tomography as a Tool for 3D Microscopy and Gene Expression Studies,” SCIENCE, vol. 296, pp. 541-545, Apr. 19, 2002.
Sharpe, J, review, “Optical Projection Tomography as a New Tool for Studying Embryo Anatomy,”J. Anat. (2003), pp. 175-181.
RH Anderson, “Close-up imaging of documents and displays with lens arrays,”Applied Optics18, 477 (1979).
Kak, A.C. and Slaney, M.,Principles of Computerized Tomographic Imaging, IEEE Press, New York, 1988.
E.G. Steward,Fourier Optics: An Introduction, 2nd ed. (Halsted Press, New York, 1987).
A. Klug and J.L. Finch, “Structure of viruses of the papilloma-polyoma type,” J. Mol. Biol., vol. 37, p. 1 (1968).
A. Klug, “Image analysis and reconstruction in the electron microscopy of biological macromolecules,” Chem. Scripta, vol. 14, p. 245 (1978).
T.C. Wedberg and J.J. Stamnes, “Recent results in optical diffraction microtomography,” Meas. Sci. Technol., vol. 7, p. 414 (1996).
Y. Li, et al., “Comparison of analog and digital Fourier transforms in medical image analysis,” J. Biomed. Optics, vol. 7, p. 255 (2002).
Y. Xu et al., “Three-dimensional diffuse optical tomography of bones and joints,” J. Biomed. Optics, vol. 7, p. 88 (2002).
H. Banda-Gamboa et al., “Spectral-Analysis of Cervical Cells Using the Discrete Fourier-Transform,” Anal. Cell. Path., vol. 5(2), pp. 85-102 (1993).
D.E. Burger, et al., “Extraction of Morphilogical Features from Biological Models and Cells by Fourier Analysis of

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