Variable molecular separator

Gas separation – Means within gas stream for conducting concentrate to collector

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Details

55386, 210656, 2101982, 422 70, B01D 1508

Patent

active

046540520

ABSTRACT:
A method and device for separating trace amounts of relatively large molecules in the gas or vapor state from a low molecular weight gas or vapor is disclosed. The method and device are particularly useful for interfacing a gas or liquid chromatograph to a mass spectrometer. The device comprises an enclosed chamber to which a vacuum system is attached. Two sample transfer columns are inserted through opposite sides in the chamber. The first column has an outer diameter smaller than the inner diameter or bore of the second column and the end of the first column may be moved into the bore of the second column. A second vacuum source is applied to the second transfer column. When a sample mixture in the gas or vapor state passes from the first column into the second column, the fractional split in the bulk or carrier stream between the two vacuum systems is accurately controlled solely by the diameters of the two columns and the extent to which the first column in inserted into the second. Also depending on the depth of insertion the larger trace sample molecules may be caused to preferentially pass into the second column and vacuum system. In general, sample enrichment of a gas stream can be accomplished at the expense of sample recovery. For chromatography/mass spectrometry applications trace sample recovery may be kept at acceptable levels while maintaining high vacuum conditions in the mass spectrometer.

REFERENCES:
patent: 3408166 (1968-10-01), Natelson
patent: 3498027 (1970-03-01), Buchtel, Jr.
patent: 3678656 (1972-07-01), Brunnee et al.
patent: 4035168 (1977-07-01), Jennings
patent: 4453954 (1984-06-01), Korb et al.

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