Variable flow rate injector

Liquid purification or separation – With means to add treating material – Chromatography

Reexamination Certificate

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Details

C210S656000, C210S101000, C210S143000

Reexamination Certificate

active

06962658

ABSTRACT:
A variable flow rate injector provides accurate, precise, and reproducible injection volumes that have low dispersion. The invention is particularly well-suited for HPLC injection volumes <500 nL but can be used to inject larger volumes and in different applications as well. Injections are performed at a first flow rate and separations are performed at a second flow rate. For improved HPLC system performance, the first flow rate is less than the second flow rate. The injector uses a variable flow rate fluid supply that allows rapid switching between flow rates desired for injection and flow rates desired for separations.

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patent: 6833068 (2004-12-01), Paul et al.
patent: 2002/0146840 (2002-10-01), Hage et al.
patent: 2003/0064008 (2003-04-01), Hage et al.
Foster, Marc D., Performance of Experimental Sample Injectors for High-Performance Liquid Chromatography Microcolumns, Journal of Chromatography (2000), p. 231-241.
Notification of Transmittal of the International Search Report and the Written Opinion of the International Searching Authority (PCT-US04/15838).

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