Vapor phase production of chlorinated pyridines from alpha-picol

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D21361

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active

047526440

ABSTRACT:
2-Chloropyridine, 2,6-dichloropyridine, 2,3,6-trichloropyridine, and 2,3,5,6-tetrachloropyridine are prepared by reacting alpha-picoline in the gas phase with choline at temperature from about 200.degree. C. in the presence of water and an amount of catalyst effective to catalyze the reaction.

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