Vanilloid receptor ligands and their use in treatments

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

Reexamination Certificate

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C544S370000, C514S253010

Reexamination Certificate

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07439360

ABSTRACT:
Therapeutic benzimidazoles and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

REFERENCES:
patent: 6444687 (2002-09-01), Stamford et al.
patent: 2004/0152690 (2004-08-01), Balan et al.
patent: 54/48763 (1979-04-01), None
patent: WO-99/31089 (1999-06-01), None
patent: WO 1999/31089 (1999-06-01), None
CA Registry No. 753435-35-7, indexed in the Registry file on STN on Sep. 29, 2004.
CA Registry No. 736915-29-0, indexed in the Registry file on STN on Sep. 1, 2004.
CA Registry No. 733726-92-6, indexed in the Registry file on STN on Aug. 27, 2004.
CA Registry No. 696583-01-4, indexed in the Registry file on STN on Jun. 20, 2004.
An English translation of JP 54-48763, 1979.
Schroder, et al., Eur J. Med Chem., “Nichtsteroidale Entz ndungshemmer.7. Entz ndungshemmende Methansulfonanilide II” 17 (2) 165-172 (1982).

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