Vanilloid receptor ligands and their use in treatments

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S374000, C514S396000, C548S146000, C548S215000, C548S300100

Reexamination Certificate

active

10775980

ABSTRACT:
Compounds having the general structureand compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

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Sycheva et al. “Compounds with potential antitubercular . . . ” CA 58:53202 (1963).
Tashika et al. “2-2-substituted-4-thiazolyl . . . ” CA 66:65472 (1967).
Hayakawa et al. “Preparation of aminoazoles . . . ” CA 139:364922 (2003).
Tashika et al. “2-(2-substituted-4-thiazolyl—benzimidazole derivatives” CA 66:65472 (1967).
JP 41 020220 B (JPN. TKKYO KOHO) Nov. 25, 1966 Caplus-RN; 14521-72-3p abstract.

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