Vancomycin haemostatic paste composition

Details Vancomycin haemostatic paste composition Vancomycin haemostatic paste composition

2006-12-05

2006-12-05

Chism, B. Dell (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S002600

Reexamination Certificate

active

07144857

ABSTRACT:
A haemostatic paste composition comprising powdered vancomycin mixed with a biocompatible carrier. The haemostatic paste composition is easily handled, adheres to a cut bone surface or an exposed bone surface, provides for effective haemostasis to prevent blood loss from a cut bone surface or an exposed bone surface, has no systemic or local adverse effect and provides bacteriostatic and bacteriocidal protection. The haemostatic paste composition is well suited for use with sternotomy incisions, but can also be used for any cut bone surface or exposed bone surface during surgery.

REFERENCES:
patent: 2004/0052841 (2004-03-01), Vogt et al.
Winkler et al., 2000, Journal of Antimicrobial Chemotherapy, vol. 26, pp. 423-428.
Halasz, Nicholas A., Wound infection and topical Antibiotics, The Surgeon's Dilemma, Arch Surg, vol. 112, Oct. 1977 pp. 1240-1244.
Vander Salm, Thomas J., et al., Reduction of sternal infection by application of topical vancomycin, J Thorac Cardiovasc Surg 1989; 98: 618-22.

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