Valepotriate hydrin containing medicines used to treat uclers an

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549396, 514927, 514926, A61K 3135

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active

048913847

ABSTRACT:
The use of valepotriate hydrins in the prevention and treatment of disorders of the gastrointestinal tract is described, together with pharmaceutical compositions containing valepotriate hydrins and certain novel valepotriate hydrins per se.

REFERENCES:
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patent: 3812154 (1974-05-01), Thies
patent: 3917651 (1975-11-01), Thies
patent: 4189323 (1980-02-01), Buhr
patent: 4239850 (1980-12-01), Kita et al.
patent: 4313930 (1982-02-01), Wischniewski et al.
patent: 4391819 (1983-07-01), Thies et al.
Patent Abstracts of Japan, Vol. 5, Number 89 (C-58) [761], June 10, 1981, Japanese Patent Application No. 56-34627.
Patent Abstracts of Japan, Vol. 5, No. 160 (C-75) [832], October 15, 1981, Japanese Patent Appl. No. 56-90011.
Tetrahedron Letters No. 15, (1976) J. Hoelzl et al., "Zur Struktur Von Drei Genuinen Valtrathydrinen Aus Valeriana Tiliaefolia", pp. 1171-1174.
Comptes rendus de l'Academie Bulgare des Sciences, No. 5, 1975, S.S. Popov et al., "Biogenetic Relationship Between Some Valepotriates", pp. 651-653.
Tetrahedron Vol. 29, No. 15, 1973, P.W. Thies, "Ueber Die Wirkstoffe Des Baldrians-X.sup.1 ", pp. 3213-3226.
Tetrahedron Vol. 24, 1968, P.O. Thies, "Die Konstitution Der Valepotriate", pp. 313-347.
P. W. Thies et al., "Assignment of Type and Location of the Acyloxy Substituents in Valepotriates via C13-NMR-Spectroscopy", Planta Medica Journal of Medicinal Plant Research, No. 1, 1981, Vol. 41, pp. 15-20.

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