Vaginal suppository for contraception, having a predetermined la

Details Vaginal suppository for contraception, having a predetermined la Vaginal suppository for contraception, having a predetermined la

1978-12-22

1982-04-06

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Gas produced in situ by chemical reaction

424 78, 424341, 424359, 424DIG14, 424DIG15, A61K 900, A61K 3109

Patent

active

043235484

ABSTRACT:
A spermicidally-active vaginal suppository consisting essentially of a solid water-soluble polymeric material which melts at body temperature, for example, a polyethylene glycol, having dispersed therein minor amounts of a spermicide, for example, p-nonylphenoxypolyethoxyethanol, a foaming agent operative when the suppository is dissolved in aqueous media to generate a foam-forming gas, for example, a mixture of a water-soluble bicarbonate and a solid weak acid, and a foam-stabilizing agent which is characterized by containing a surfactant, which is effective to reduce the surface tension of water to less than 45 dynes per centimeter, for example, sodium lauryl sulfate, and lactalbumin.

REFERENCES:
patent: 2467884 (1949-04-01), Elias
patent: 3875073 (1975-04-01), Deininger et al.
patent: 3876757 (1975-04-01), Scherm

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