Vaginal pharmaceutical compositions and methods for...

Details Vaginal pharmaceutical compositions and methods for... Vaginal pharmaceutical compositions and methods for...

2004-09-22

2008-11-25

Padmanabhan, Sreeni (Department: 1617)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S398000, C424S430000

Reexamination Certificate

active

07456207

ABSTRACT:
Vaginal pharmaceutical compositions are described. These compositions contain (i) an active pharmaceutical ingredient selected from the group consisting of antimicrobial imidazoles and mixtures thereof, and (ii) a polysaccharide, wherein the pH of the composition is greater than 4.25 and less than about 8. In particularly preferred compositions, the active pharmaceutical ingredient includes metronidazole and the polysaccharide includes hypromellose. These compositions can be applied to vaginal tissue for treatment of various diseases, such as bacterial vaginosis, or for prophylaxis.

REFERENCES:
patent: 4837378 (1989-06-01), Borgman
patent: 5536743 (1996-07-01), Borgman
patent: 5536744 (1996-07-01), Okumura et al.
patent: 5840744 (1998-11-01), Borgman
patent: 6348203 (2002-02-01), Goodman et al.
patent: 2003/0064103 (2003-04-01), Lin et al.
patent: 2003/0119783 (2003-06-01), Chang et al.
patent: 747045 (1996-12-01), None
patent: 2199495 (1988-07-01), None
patent: 80363 (1983-02-01), None

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