Vaccinia virus containing DNA sequences encoding herpesvirus gly

Details Vaccinia virus containing DNA sequences encoding herpesvirus gly Vaccinia virus containing DNA sequences encoding herpesvirus gly

1990-04-04

1994-08-16

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Vector, per se

4351723, 135 32, C12N 1500

Patent

active

053386833

ABSTRACT:
What is described is a recombinant poxvirus, such as vaccinia virus, fowlpox virus and canarypox virus, containing foreign DNA from herpesvirus. In one embodiment, the foreign DNA is expressed in a host by the production of a herpesvirus glycoprotein. In another embodiment, the foreign DNA is expressed in a host by the production of at least two, particularly two or three, herpesvirus glycoproteins. What is also described is a vaccine containing the recombinant poxvirus for inducing an immunological response in a host animal inoculated with the vaccine. By the present invention, the barrier of maternal immunity in a newborn offspring can be overcome or avoided.

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