Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1992-02-11
1993-12-28
Furman, Keith C.
Drug, bio-affecting and body treating compositions
Lymphokine
530350, 530395, 530806, 435 693, A61K 3900
Patent
active
052737446
ABSTRACT:
This invention relates to the development of a vaccine against Theileria parva, which is a protozoan parasite infecting cattle in Africa. The invention specifically relates to the use of the 67 kDa glycoprotein from the surface of the T. parva sporozoite as an immunogen for inducing immunoprotection against T. parva in bovine species. This 67 kDa antigen is produced using recombinant genetics. Plasmids containing nucleic acid segments encoding the antigen, host cells containing the nucleic acid segments and recombinant methods for producing the antigen are part of this invention.
REFERENCES:
patent: 4020151 (1977-04-01), Bolz et al.
patent: 4394443 (1983-07-01), Weissman et al.
patent: 4713366 (1987-12-01), Stevens
patent: 4835260 (1989-03-01), Shoemaker
patent: 5006334 (1991-04-01), Stevens
Williamson, S., et al., "Theileria annulata sporozoite surface antigen expressed in Escherichia coli elicits neutralizing antibody," Proc. Natl. Acad. Sci. USA, 86:4639-4643 (Jun. 1989).
Scoper, R. K. 1987, Protein Purification, Springer-Verlag, New York, pp. 167-172.
Aebersold et al. 1986. In Peeter; R. (ed.). Protides of the Biological Fluid Proceedings of the Collogium, 34; Brussels, Belgium Pergaman Press, Oxford, England. pp. 715-718.
Lerner, R. A. 1982. Nature 299:592-596.
Anon. 1989. Proc. of a Workshop on East Coast Fern Immunigation, T. T. Dolan (ed.) NAIROB, Kenya, pp. 187-188.
Creighton, T. E. 1983, Protein:Structure and Molecular Principles, W. H. Freeman and Company, New York, N.Y., pp. 93-98.
Pongor, S. 1987. Methods in Enzymology 154:450-473.
Bowie et al. 1990. Science 247:1306-1310.
Iams Keith
Musoke Anthony J.
Nantulya Vinand M.
Nene Vish
Furman Keith C.
International Laboratory for Research on Animal Diseases
LandOfFree
Vaccines for the protection of animals against theileria infecti does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Vaccines for the protection of animals against theileria infecti, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vaccines for the protection of animals against theileria infecti will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1541239