Vaccines for diseases of fish

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

Reexamination Certificate

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C424S093200, C424S093400, C424S234100, C424S817000, C424S184100

Reexamination Certificate

active

07740864

ABSTRACT:
Fish are immunized by a mass vaccination method, such as by immersion in water containing an attenuated strain of a pathogenic bacterium that does not effectively cause disease in fish when the non-attenuated pathogenic bacterium is exposed to the fish by immersion. An illustrative example of the method is for immunizing against coldwater disease caused byFlavobacterium psychrophilum, which may be attenuated by serial passage in media containing increasing amounts of an antibiotic, such as rifampicin.

REFERENCES:
patent: 6019981 (2000-02-01), Klesius
patent: 6991793 (2006-01-01), Shoemaker
patent: 7067122 (2006-06-01), Evans
patent: 2004/0175407 (2004-09-01), McDaniel
patent: 2004/0234535 (2004-11-01), Shoemaker
patent: 2005/0283001 (2005-12-01), Schweizer
patent: 2006/0073167 (2006-04-01), Oshima
LaFrentz et al. In: Proceedings of the 48th Western Fish Disease Workshop and AFS Fish Health Section Annual Meeting, Jackson Lake Lodge, Grand Tatin National Park, pp. i-vii and p. 23, Jun. 4-6, 2007.
O'Farrell et al. Diseases of Aquatic Organisms 43: 199-209, Dec. 2001.
Daly et al. Diseases of Aquatic Organisms 44: 121-126, 2001.

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