Vaccines for counteracting inhibition of neutrophil degranulatio

Drug – bio-affecting and body treating compositions – Lymphokine

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424 92, 424 85, 530405, 530406, 530363, A61K 3902, A61K 39385

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active

047013230

ABSTRACT:
Vaccines for counteracting inhibition of neutrophil degranulation by pathogenic cellular microorganisms comprise one or more purines conjugated to antigenic carriers. The purines include adenine and/or guanine in the form of a base, nucleoside, or nucleotide. The vaccines can be used with cattle to increase resistance to infections by Brucella abortus (brucellosis) and/or Haemophilus somnus (thromboembolic meningoencephalitis) and related symptomatic complex.

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Riches et al., (1985), J. Leukocyte Biol., 37:545-557.

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