Vaccines containing ribavirin and methods of use thereof

Details Vaccines containing ribavirin and methods of use thereof Vaccines containing ribavirin and methods of use thereof

2007-08-28

2007-08-28

Campell, Bruce R. (Department: 1648)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

C424S228100

Reexamination Certificate

active

10719619

ABSTRACT:
The present invention relates to compositions and methods for enhancing the effect of vaccines in animals, such as domestic, sport, or pet species, and humans. More particularly, the use of Ribavirin as an adjuvant to a vaccine protocol and compositions having Ribavirin and an antigen are described.

REFERENCES:
patent: 4215051 (1980-07-01), Schroeder et al.
patent: 4376110 (1983-03-01), David et al.
patent: 4486530 (1984-12-01), David et al.
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4818540 (1989-04-01), Chien et al.
patent: 4873191 (1989-10-01), Wagner et al.
patent: 4946778 (1990-08-01), Ladner et al.
patent: 4950647 (1990-08-01), Robins et al.
patent: 4965188 (1990-10-01), Mullis
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5290678 (1994-03-01), Jackowski
patent: 5322770 (1994-06-01), Gelfand
patent: 5350671 (1994-09-01), Houghton et al.
patent: 5371017 (1994-12-01), Houghton et al.
patent: 5372928 (1994-12-01), Miyamura et al.
patent: 5412087 (1995-05-01), McGall et al.
patent: 5585258 (1996-12-01), Houghton et al.
patent: 5589466 (1996-12-01), Felgner et al.
patent: 5593972 (1997-01-01), Weiner et al.
patent: 5597691 (1997-01-01), Houghton et al.
patent: 5604105 (1997-02-01), Jackowski
patent: 5670152 (1997-09-01), Weiner et al.
patent: 5670153 (1997-09-01), Weiner et al.
patent: 5679342 (1997-10-01), Houghton et al.
patent: 5683864 (1997-11-01), Houghton et al.
patent: 5698390 (1997-12-01), Houghton et al.
patent: 5710008 (1998-01-01), Jackowski
patent: 5712087 (1998-01-01), Houghton et al.
patent: 5712088 (1998-01-01), Houghton et al.
patent: 5712145 (1998-01-01), Houghton et al.
patent: 5714596 (1998-02-01), Houghton et al.
patent: 5728520 (1998-03-01), Weiner et al.
patent: 5739118 (1998-04-01), Carrano et al.
patent: 5744358 (1998-04-01), Jackowski
patent: 5747274 (1998-05-01), Jackowski
patent: 5756312 (1998-05-01), Weiner et al.
patent: 5766845 (1998-06-01), Weiner et al.
patent: 5767097 (1998-06-01), Tam
patent: 5847101 (1998-12-01), Okayama et al.
patent: 5856437 (1999-01-01), Miyamura et al.
patent: 5863719 (1999-01-01), Houghton et al.
patent: 5871903 (1999-02-01), Miyamura et al.
patent: 5879904 (1999-03-01), Brechot et al.
patent: 5885799 (1999-03-01), Houghton et al.
patent: 5932556 (1999-08-01), Tam
patent: 5942234 (1999-08-01), Ralston et al.
patent: 5959092 (1999-09-01), Miyamura et al.
patent: 5968775 (1999-10-01), Houghton et al.
patent: 5989905 (1999-11-01), Houghton et al.
patent: 6027729 (2000-02-01), Houghton et al.
patent: 6056961 (2000-05-01), Lavie et al.
patent: 6060068 (2000-05-01), Doyle et al.
patent: 6063380 (2000-05-01), Chedid et al.
patent: 6063772 (2000-05-01), Tam
patent: 6071693 (2000-06-01), Cha et al.
patent: 6074816 (2000-06-01), Houghton et al.
patent: 6074846 (2000-06-01), Ralston et al.
patent: 6074852 (2000-06-01), Ralston et al.
patent: 6096541 (2000-08-01), Houghton et al.
patent: 6130326 (2000-10-01), Ramasamy et al.
patent: 6150087 (2000-11-01), Chien
patent: 6150337 (2000-11-01), Tam
patent: 6153421 (2000-11-01), Yanagi et al.
patent: 6171782 (2001-01-01), Houghton et al.
patent: 6190864 (2001-02-01), Cha et al.
patent: 6194140 (2001-02-01), Houghton et al.
patent: 6214583 (2001-04-01), Cha et al.
patent: 6235888 (2001-05-01), Pachuk et al.
patent: 6274148 (2001-08-01), Ralston et al.
patent: 6297370 (2001-10-01), Cha et al.
patent: 6303292 (2001-10-01), Weiner et al.
patent: 6312889 (2001-11-01), Houghton et al.
patent: 6514731 (2003-02-01), Valenzuela et al.
patent: 6541011 (2003-04-01), Punnonen et al.
patent: 6555114 (2003-04-01), Leroux-Roels et al.
patent: 6653125 (2003-11-01), Donnelly et al.
patent: 2002/0004048 (2002-01-01), Ralston et al.
patent: 2002/0165172 (2002-11-01), Sallberg et al.
patent: 2002/0183508 (2002-12-01), Maertens et al.
patent: 2002/0187945 (2002-12-01), Tam
patent: 2003/0007977 (2003-01-01), Wheeler et al.
patent: 2003/0008274 (2003-01-01), Maertens et al.
patent: 2003/0032005 (2003-02-01), Maertens et al.
patent: 2003/0044774 (2003-03-01), Valenzuela et al.
patent: 2003/0064360 (2003-04-01), Maertens et al.
patent: 2004/0092730 (2004-05-01), Sallberg
patent: 0 388 232 (1990-09-01), None
patent: 0 414 475 (1991-02-01), None
patent: 0 450 931 (1996-06-01), None
patent: 0 543 924 (1997-06-01), None
patent: 0 842 947 (1998-05-01), None
patent: 0 693 687 (1999-07-01), None
patent: 0 556 292 (1999-12-01), None
patent: 1 034 785 (2000-09-01), None
patent: 0 318 216 (2001-08-01), None
patent: WO90/15070 (1990-12-01), None
patent: WO91/15575 (1991-10-01), None
patent: WO92/10092 (1992-06-01), None
patent: WO92/19743 (1992-11-01), None
patent: WO93/00365 (1993-01-01), None
patent: WO93/06126 (1993-04-01), None
patent: WO94/11530 (1994-05-01), None
patent: WO94/12305 (1994-06-01), None
patent: WO94/16737 (1994-08-01), None
patent: WO95/11995 (1995-05-01), None
patent: WO96/09805 (1996-04-01), None
patent: WO96/28162 (1996-09-01), None
patent: WO96/33739 (1996-10-01), None
patent: WO97/12043 (1997-04-01), None
patent: WO97/26883 (1997-07-01), None
patent: WO97/29212 (1997-08-01), None
patent: WO97/31256 (1997-08-01), None
patent: WO97/47358 (1997-12-01), None
patent: WO98/16184 (1998-04-01), None
patent: WO98/16186 (1998-04-01), None
patent: WO98/30223 (1998-07-01), None
patent: WO98/34640 (1998-08-01), None
patent: WO98/37180 (1998-08-01), None
patent: WO99/04008 (1999-01-01), None
patent: WO99/28482 (1999-06-01), None
patent: WO 00/44388 (2000-08-01), None
patent: WO 01/38360 (2001-05-01), None
patent: WO 01/96875 (2001-12-01), None
patent: WO 03/031588 (2003-04-01), None
Steigerwald-Mullen et al. J. Virol. 2000, vol. 74, No. 15, pp. 6748-6759.
Heagy et al. J. Clin. Invest. 1991, vol. 87, pp. 1916-1924.
Hahm et al., “NS3-4A of Hepatitis C Virus is a Chymotrypsin-Like Protease,” Journal of Virology, The American Society for Microbiology, 69(4):2534-2539 (1995).
AASLD Abstracts 940, “Hepatitis C Virus NS54 Sequence Confirugation does not Predict Response to Induction Interferon Plus Ribavirin,”Hepatology, p. 394A (2000).
Abrignani et al., “Perspectives for a vaccine against hepatitis C virus,” Journal of Hepatology, 31: (suppl. 1):259-263 (1999).
Bartenschlager et al., “Substrate Determination for Cleavage in cis and in trans by the Hepatitis C Virus NS3 Proteinase,”Journal of Virology, pp. 196-205, (1995).
Chen et al., “Human and Murine Antibody Recognition is Focused on the ATPase/Helicase, but not the Protease Domain of the Hepatitis C Virus Nonstructural 3 Protein,”Hepatology, 28(1):219-224 (1998).
Chen et al., “Detection of Hepatitis C Virus RNA in the Cell Fraction of Saliva Before and After Oral Surgery,”J. Med. Virol., 43:223-226 (1995).
Chiang et al., “Enhancement of hepatitis C virus core antigen-specific type 1 T helper cell response by ribavirin correlates with the increased level of IL-2,”Vaccine Strategies Against Microbial Pathogens, 42.11-42.16, p. A949 (date unknown).
Cotonat et al., “Pilot Study of Combination Therapy with Ribavirin and Interferon Alfa for the Retreatment of Chronic Hepatitis B e Antibody-Positive Patients,”Hepatology, 31(2):502-506 (2000).
Cramp et al., “Hepatitis C Virus-Specific T-Cell Reactivity During Intereron and Ribavirin Treatment in Chronic Hepatitis C,”Gastron. Enterol., 118:346-355 (2000).
Encke et al., “DNA Vaccines,”Intervirology, 42:117-124, (1999).
Encke et al., “Genetic Immunization Generates Cellular and Humoral Immune Responses Against the Nonstructural Proteins of the Hepatitis C Virus in a Murine Model”,Journal of Immunology, 161:4917-4923 (1998).
Diepolder et al., “Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection,”Lancet, 346(8981):1006-1007.
Fang et al., “Ribavirin enhancement of hepatitis C virus core antigen-specific type 1 T helper cell response correlates with the increased IL-12 level,”Journal of Hepatology, 33(5):791-798 (20

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