Vaccines containing bacteria attenuated by mutations in two gene

Details Vaccines containing bacteria attenuated by mutations in two gene Vaccines containing bacteria attenuated by mutations in two gene

1995-05-24

1998-09-22

Minnifield, Nita

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

4241841, 4242581, 4242781, 435 693, 4351721, 4351723, 435243, 435245, 4352523, A61K 3902, A61K 39112, C12N 1500, C12N 100

Patent

active

058111050

ABSTRACT:
An attenuated microorganism harboring two mutated genes, each of which is located in the organisms aromatic pathway is provided. These organisms can usefully form the basis of a vaccine. They can be genetically engineered so as to express antigens from other pathogens and thus form the basis of a range of multi-valent vaccines.

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