Vaccines against animal parasitic nematodes

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 697, 4352523, 4353201, 536 231, 536 234, 536 235, 536 237, 4242651, 4241841, 4241301, 530300, 530350, 5303871, 5303886, C12N 1500, C07H 2104, A61K 3900

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058437061

ABSTRACT:
The invention disclosed relates to proteins derived from parasitic nematodes that confer protective immunity against infection by parasitic nematodes, to nucleotide sequences encoding those proteins, to recombinant molecules containing such sequences, to host cells transformed with such recombinant molecules and methods for the production of the nucleotide sequences, recombinant molecules and hosts. The invention also relates to vaccines comprising proteins of the invention together with suitable carriers or diluents and to antibodies raised against proteins of the invention.

REFERENCES:
patent: 4670384 (1987-06-01), Gamble et al.
patent: 4879213 (1989-11-01), Fox et al.
patent: 5021342 (1991-06-01), Green et al.
Lazar et al Mol. Cell. Biol. 1988 vol. 8, No. 3, 1247-1252.
Burgess et al J. Cell. Biol. 1990 vol. 111, 2129-2138.
Siberstein et al., "Antigenes for Trichinella spiralis That Induce a Protective Response in the Mouse", J. Immunology, 132 pp. 898-904 (1984).
Hotez et al., "Isolation, Cloning and Expression of a Protease From Ancylostoma Hookworms", Journal of Cellular Biochemistry, UCLA Symposia on Molecular and Cellular Biology, Suppl. 10A, p. 132 (1986).
Hotez et al., "Isolation and Characterization of Proteolytic Enzyme From the Adult Hookworm Ancylostoma caninum", The Journal of Biological Chemistry, 260, pp. 7343-7348, (1985).
Laemmli, U.K. (1970), "Cleavage of structural proteins during the assembly of the head of bacteriophage T4", Nature 227 680-685.
Maryama et al. (1986), "Codon usage tabulated from the GenBank genetic sequence data", Nucleic Acids Research 14 r151-r197.
May, R.B. (1985), "Evolution of pesticide resistance" Nature 315 12-13.
Payne, J.W. (1973), "Polymerization of proteins with glutaraldehyde: soluble molecular weight markers" Biochem. J. 135 867-873.
Racusen, D. (1979), "Glycoprotein detection in polyacrylamide get with thymol and sulfuric acid", Analytical Biochemistry 99 474-476.
Rubin et al. (1983), "Two-dimensional polyacrylamide gel electrophoresis of membrane proteins" Methods in Enzymology 96 184-193.
Ruther, U. et al. (1983), "Easy identification of CDNA clones". EMBO Journal 2 1791-1794.
Sanger, R. et al. (1980), "Cloning in single bacteriophage as an aid to rapid DNA sequencing", J. Mol. Biol, 143 161-178.
Towbin, H. et al. (1979), "Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications", PNAS 76 4350-4353.
Wallace, R. B. et al. (1980), "Directed deletion of yeast transfer RNA intervening sequence", Science 209 1396-1400.
Yanisch-Perron, C. et al. (1985), "Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors", Gene 33 103-119.
Vieira J., et al. (1982), "The puC plasmids, and M13mp17-derived system for insertion mutagenesis and sequencing with synthetic universal primers", Gene 19 259-268.
Reed, K.C. "Nucleic Acid Hybridizations with DNA Bound to Zeta-Probe Membrane", BIO-RAD Bulletin 1234.
Benton et al. (1977), "Screening Lanbda gt Recombinant clones by hybridization to single plagues in situ", Science 196: 180-182.
Dineen, J.K. (1984), "Immunological control of helminthiases by genetic manipulation of host and parasite", Immunogenetic approaches to the control of endoparasites with particular reference to parasites of sheep (J.K. Dineen and P.M. Otteridge, eds.) CSIRO, Australia, pp. 1-9.
O'Donnell, I.J. (1973), "A search for a simple keratin fractionatin and peptide mapping of proteins for feather keratins", Aust. J. Biol. Sci. 26 401-413.
Hunke et al., J. Biol. Chem. 262: 17370-17373, 1987, Database search (1) only.
Hunke et al., Gene 45: 211-214, 1986.
Maniatis et al., "Molecular Cloning", A Laboratory Manual 1982, Cold Spring Harbor Chapter 6-10.
Selkirk et al., Parasitology 1986 91: 515-538.
Noble et al., Parasitology, 5th Ed. 1982.
Hanke et al., Database search, Gene: 45: 211-214, 1986.
D.B. Adams et al. (1984), "Basis for the development of vaccines for control of diseases produced by metazoan parasites", Rural Sciences 6 67-74.
Dineen et al., (1977), "The role of immunologically specific and non-specific components of resistance in cross-protection to intestinal nematodes", Journal for Parasitology 7 211-215.
Dineen and Wagland, (1982), "Immunoregulation of parasites in natural host-parasite system--with special reference to the gastrointestinal nematodes of sheep", Biology and Control of Endoparasites (L.E.A. Symons et al. eds.), Academic Press, pp. 297-323.
J.K. Dineen, (1984), "Immunological control of helminthiases by genetic manipulation of host and parasite", Immunologenetic approaches to the control of endoparasites with particular reference to parasites of sheep (J.K. Dineen et al., eds.) CSIRO, Australia, pp. 2-8.
A.P. Feinberg et al., (1984), "A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity", Analytical Biochemistry 137 266-267.
M. Hattori et al., (1986), "Dideoxy sequencing method using denatured plasmid templates", Analytical Biochemistry 152 232-238.
J.G. Howe et al. (1981), "A sensitive immunoblotting method for measuring protein synthesis initiation factor levels in lysates of Escherichia coli", Journal of Biological Chemistry 256 12836-12839.
T.V. Huynh et al., (1985), "Construction and screening of cDNA libraries in lambda gt10 and lambda gt11", pp. 49-78, DNA Cloning vol. 1 (D.M. glover, ed.).
F.D.A. Johnson et al., (1984), "Improved technique utilizing non fat dry milk for analysis of proteins and nucleic acids transferred to nitrocellulose", Gene Anal. Tech. 1:3-8.
P. Kohler, (1986), "Progress in molecular parasitology", Eperientia 42 377-386.
N.M. McKern et al, (1985), "Primary structure of pilin protein for Bacteroides nodosus strain 216: comparison with the corresponding protein from strain 198", Journal of General Microbiology 131 1-6.
Munn et al., (1983), "Endotube brush border complexes dissected from the intestines of Haemonchus contortus and Ancyclostoma caninum", Parasitology 87 129-137.
J.T.M. Neilson, (1975), "Failure to vaccinate lambs against Haemonchus contortus with functional metabolic antigens identified by immunoelectrophoresis", Int. J. Parasitology 5 427-430.
Neilson et al., (1987), "Partial protection of lambs against Haemonchus contortus by vaccination with a fractionated preparation of the parasite", Veterinary Parasitology 23 211-221.
O'Donnell, (1973), "A search for a simple keratin fractionatin and peptide mapping of proteins from feather keratins", Aust J. Biol. Sci 6 401-413.
O'Donnell et al., (1985), "Attempts to probe the antigens and protective immunogens of Trichostrongylus colubriformus in immunoblots with sera from infected and hperimmune sheep and high and low responder guinea pigs", Int. J. Parasitology 15 129-136.
Rothwell et al., (1974), "Vaccination against the nematode Trichostrongylus clubriforms -1. Vaccination of guinea pigs and worm homogenates and soluble products released during in vitro maintenance", Int. Journal for Parasitology 4 293-299.
Rothwell et al., (1977), "Comparison of the kinetics of expulsion of Trichostrongylus colibriformus from previously uninfected, reinfected and vaccinated guinea pigs", J. Parasitology 63 761-762.
Rothwell, (1978), "Vaccination against the nematode Trichostrongylus colubriformis - III. Some observations on factors influencing immunity to infection in vaccinated guinea pigs", Int. J. for Parasitology 8 33-37.
Silberstein et al., (1985), "Effects on Trichinella spiralis of host response to purified antigens", Science 227 948-950.
Stearne et al., (1985), "The murine plasma cell antigen PC-1: purification and partial amino acid sequence", The Journal of Immunology 134 443-448.
Ulrich et al., "Isolation of the human insulin-like growth factor I gene using a single synthetic DNA probe", The EMBO J.
Nilsen et al., "Cloning and Characterization of a Potentially Protective Antigen Lymphatic Filariasis", Proc. Natl. Acad. Sci. (USA), 85 (10) 1988 Coden USA, pp. 3604-3607.
Munn et al., "Vaccination of Young Lambs By Means of a Protein Fraction Extracted From Adult Haemo

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