Vaccine stabilizer containing L-glutamic acid and L-arginine

Details Vaccine stabilizer containing L-glutamic acid and L-arginine Vaccine stabilizer containing L-glutamic acid and L-arginine

1980-07-30

1982-07-06

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424 89, 435235, A61K 3912, A61K 39165, A61K 3913, A61K 39245

Patent

active

043383351

ABSTRACT:
An improved stabilized liquid live viral vaccine contains a live virus, partially hydrolyzed gelatin, a monosaccharide or disaccharide, a cell culture medium, L-glutamic acid, L-arginine and sufficient physiologically acceptable acidic buffer to maintain the pH at from about 6.0 to about 6.5.

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McAleer at al. Chem. Abstr. 95 #68007Z (1981) of Eur. Pat. Appl. 28,563, May 13, 1981, "Stabilizer For Liquid Vaccines".
Merck and Co., Inc. Chem. Abstr. 92 #135397e (1980) of Neth. Appl. 78 03891, Oct. 16, 1979, "Vaccine Stabilizer".
McAleer et al. Chem. Abstr. 93 #80039c (1980) of S. African 78 02,123, Nov. 28, 1979, "Vaccine Stabilizer".
Chem. Absts. 76:144799j (1972).
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Chem. Absts. 80:41031f (1974).
Contract AID/afr-c-1192, Aug. 28, 1978.

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