Vaccine stabilizer containing L-glutamic acid and L-arginine

Details Vaccine stabilizer containing L-glutamic acid and L-arginine Vaccine stabilizer containing L-glutamic acid and L-arginine

1981-03-10

1982-06-29

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Lymphokine

435235, A61K 3912, A61K 39165, A61K 3913, A61K 39245

Patent

active

043372422

ABSTRACT:
An improved stabilized liquid live viral vaccine contains a live virus, partially hydrolyzed gelatin, a monosaccharide or disaccharide, a cell culture medium, L-glutamic acid, L-arginine and sufficient physiologically acceptable acidic buffer to maintain the pH at from about 6.0 to about 6.5.

REFERENCES:
patent: 3783098 (1974-01-01), Calnek et al.
patent: 4147772 (1979-04-01), McAleer et al.
patent: 4273762 (1981-06-01), McAleer et al.
McAleer et al., Chem. Abstr. 95 #68007z(1981) of Eur. Pat. Appl. 28, 563 13 May 1981 "Stabilizer for Liquid Vaccines".
Merck and Co. Inc. Chem. Abstr. 92 #135397e(1980) of Neth. Appl. 78, 03891 16 Oct. 1979, "Vaccine Stabilizer".
McAleer et al., Chem. Abstr. 93 #80039c(1980) of S. African 78 02123, 28 Nov. 1979, "Vaccine Stabilizer".

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