Vaccine production process

Details Vaccine production process Vaccine production process

1975-09-04

1977-09-20

Rosen, Sam

Textiles: fiber preparation

195 14, 195 18, 424 89, C12K 700, C12B 300, A61K 3926

Patent

active

040494942

ABSTRACT:
A viral vaccine effective against foot-and-mouth disease is produced without the use of serum or non-chemically defined serum substitutes. A viable culture of baby hamster kidney cells in a heat-stable, glutamine-free, serum-free, chemically defined medium is inoculated with one of the seven major immunological types of foot-and-mouth disease viruses to which the cells are susceptible, the virus is propagated in the culture and the virus harvest is recovered therefrom.

REFERENCES:
patent: 3196077 (1965-07-01), Pilz et al.
patent: 3836626 (1974-09-01), Lavender
Willmer-Cells and Tissues in Culture, vol. 1 (1965) pp. 299-301.

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