Vaccine manufacture for active immunization containing hepatitis

Details Vaccine manufacture for active immunization containing hepatitis Vaccine manufacture for active immunization containing hepatitis

1977-02-24

1978-10-03

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

195 15, A61K 3912, C12K 700

Patent

active

041184785

ABSTRACT:
A process for preparing a vaccine containing unprecipitated filaments and hepatitis B Dane particle specific antigens by removal from a blood serum of other proteinaceous matter such that the serum contains less than 10% proteinaceous matter other than that associated with hepatitis B surface antigen or the filament or Dane particle specific antigen. Any virus present is inactivated, and the antigenous mass is diluted with a physiologically acceptable medium.

REFERENCES:
patent: 4017360 (1977-04-01), Bertland et al.
patent: 4024243 (1977-05-01), McAleer et al.

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