Vaccine for immunization of swine against Bordetella bronchisept

Details Vaccine for immunization of swine against Bordetella bronchisept Vaccine for immunization of swine against Bordetella bronchisept

1976-03-29

1977-04-05

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

A61K 3902

Patent

active

040162532

ABSTRACT:
A strain of Bordetella bronchiseptica (ATCC No. 31123) is employed in the form of killed whole cells for parenteral administration to swine or other animals subject to Bordetella bronchiseptica infection. Swine can be effectively protected against development of the turbinate atrophy associated with Bordetella bronchiseptica infection by parenterally administering to young pigs from 1 to 3 doses of a vaccine containing from 10.sup.9 to 10.sup.11 cells of said strain. The vaccine can also be administered to breeding sows prior to farrowing for at least partial protection of the offspring.

REFERENCES:
farrington D. O. et al., "Resistance to Bordetella rhinitis", pp. 44-52 Proceedings, Geo. A. Young Conference on Advances in Swine Repopulation and the Thirteenth Annual Nebraska SPF Conference, Lincoln, Nebraska, July 23-24, 1973.
Harris D. L. et al., Amer. J. Vet. Res. 33(10):1975-1984, Oct. 1972, "Immunization of Pigs Against Bordetella bronchiseptica Infection by Parenteral Vaccination".
Harris, D. L. et al., Amer. J. Vet. Res. 30:1161-1166, July 1969, "Nasal and Tracheal Resistance of Swine Against Re-infection by Bordetella bronchiseptica".

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