Vaccine for enhanced production of IgA antibodies

Details Vaccine for enhanced production of IgA antibodies Vaccine for enhanced production of IgA antibodies

1995-03-08

1999-02-23

Chan, Christina Y.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

4241841, 4241931, 4241941, 4242781, 424 852, 424 854, 42419711, A61K 3900, A61K 3818, A61K 3819, A61K 3902

Patent

active

058740856

ABSTRACT:
The invention describes compositions and methods for optimizing IgA class switching in B cells. The compositions comprise a multivalent antigen receptor crosslinker, CD40 ligand or lipopolysaccharide, and the cytokines TGF-.beta., IL-4, and either IL-5 or IL-2. Methods of using the compositions are also described.

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