Vaccine for animal respiratory diseases

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

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A61K 3902

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041713540

ABSTRACT:
An improved vaccine and method for immunizing cattle to Shipping Fever Complex type Bovine Respiratory Disease (BRD) which employs an intradermally administered vaccine containing a live culture of Pasteurella sp., particularly, Pasteurella hemolytica. Innoculation is carried out before the animals are subjected to stress factors, including weaning and transportation to feedlots. Also described is a method for preparing the vaccine by incubation of P. hemolytica within an infusion broth.

REFERENCES:
patent: 3855408 (1974-12-01), Maheswaran
Difco Laboratories Catalog, Nov. 1968, pp. 370, 54, 474-475, 109, Detroit, Michigan.
Gale et al., "Studies on Shipping Fever of Cattle, I, Experimental Exposure of Cattle with Various Cultures of Pasteurella", American Journal of Veterinary Research 19, (1958), pp. 815-817.
Merck Veterinary Manual, Fourth Edition, 1973, pp. 1407-1410.
Remington's Practice of Pharmacy, Tenth Edition, Mack Publishing Co., pp. 1209-1212.
Baldwin et al., "Experimental Infection of Calves with Myxovirus Parainfluenza 3 and Pasteurella Hemolytica", American Journal of Veterinary Research, 28, (1967), pp. 1773-1782.

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