Vaccine comprising fowlpox virus recombinants expressing the env

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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4241991, 435 693, 4351723, 4352351, A61K 3921, C12N 1548

Patent

active

054035821

ABSTRACT:
A recombinant fowlpox virus is provided which is useful as a vaccine for protection against avian reticuloendo-theliosis virus-associated diseases. In a specific embodiment, the recombinant virus expresses a gene encoding an envelope glycoprotein of spleen necrosis virus under the control of a poxvirus promoter, inserted in a nonessential region of the fowlpox virus genome.

REFERENCES:
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patent: 5187087 (1993-02-01), Sondermeijer et al.
patent: 5208024 (1993-03-01), Van Den Bosch
Federspiel et al, Virology 173(1): 167-177, 1989.
Witter et al, Avian Diseases 33:226-235, 1989.
Earl et al, Science 234:728-731, 1986.
Fadly et al, Infection and Immunity 37(3):1156-1161, 1982.
Bennett et al, Virus Res 8(1) pp. 73-77, 1987.

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