Vaccine compositions and adjuvant

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Testing efficacy or toxicity of a compound or composition

Reexamination Certificate

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C424S009100, C424S184100, C424S185100, C424S248100, C435S174000

Reexamination Certificate

active

07731939

ABSTRACT:
The immune response of an animal to a target immunogen may be enhanced by use of a novel adjuvant which includes low concentrations of killed cells ofMycobacterium aviumsubspeciesaviumin combination with mineral oil. The adjuvant may be used in vaccine compositions for the immunization of an animal against any target immunogen, and is particularly preferred for use with immunocontraceptive vaccines such as GnRH and PZP immunocontraceptive vaccines.

REFERENCES:
Kondo, Y. et al. “Elevated adjuvanticity of non-acid-fast Mycobacteria”. Infection and Immunity, vol. 26, No. 1, pp. 19-24, Oct. 1979.
Miller, L.A., et al. “Immunocontraception of white-tailed deer with GnRH vaccine”, American Journal of Reproductive Immunology, vol. 44, pp. 266-274, 2000.

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