Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1998-01-16
2000-04-25
Scheiner, Laurie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4241841, 4241861, 4242041, 4242291, 4242781, 435236, 435237, A61K 39245
Patent
active
060541318
ABSTRACT:
The present invention discloses a new immunogenic composition for Herpes Simplex comprising a whole live HSV-2 virus having the oncogene deleted. Methods of using the vaccine composition are also included.
REFERENCES:
patent: 4347127 (1982-08-01), Duttera et al.
patent: 4452734 (1984-06-01), Larson et al.
patent: 4554159 (1985-11-01), Roizman et al.
patent: 5171568 (1992-12-01), Burke et al.
patent: 5219567 (1993-06-01), Skinner et al.
PCT International Search Report Dated May 27, 1999 and references.
M. Waxhsman, L. Aurelian, J.C.R. Hunter, M.E. Perkus Expression of herpes simplex virus glycoprotein D on Bioscience Reports, 8, 323-334, 1988.
M. Wachsman, J.H. Luo, L. Aurelian, E. Paoletti Protection from herpes simplex virus type 2 is associ Vaccine, 10, 447-453, 1992.
M. Wachsman, L. Aurelian, C.C. Smith, M.E. Perkus and Regulation of expression of herpes simplex virus (HSV Journal of Infectious Diseases 159, 625-634, 1989.
Mary.sub.-- Ann Mullen, Dolores M. Ciufo, Gary S. Hayward Mapping of intracellular localization domains and evi Journal of Virology 68, 3250-3266, 1994.
Stephen A. Rice, Melissa C. Long, Vivian Lam Charlott RNA polymerase II is aberantly phosphorylated and loc Journal of Virology 68, 988-1001 1994.
Mary Ann Hardwicke, Rozanne M. Sandri.sub.-- Goldin The herpes simplex virus regulatory protein IPC27 Journal of Virology 68, 4797-4810, 1994.
Peter O'Hare and Gary S. Hayward Evidence for a direct role for both the 175,000 and Journal of Virology, 53, 751-760, 1985.
Chu-Pei Feng, Michael Kulka, Cynthia Smith and Laure Herpes simplex virus-mediated activation of human imm Antisense and Nucleic Acid Drug Development 6, 25-351996.
Bruce C. Strnad and Laure Aurelian Proteins of herpesvirus type 2 Virology, 73, 244-258, 1976.
Robert W. Honess, Bernard Roizman Regulation of herprsvirus macromolecular synthesis Journal of Virology, 14, 8-19, 1974.
Kent W. Wilcox, Alexander Kohn, Elena Sklyanskaya and Herpes simplex virus phosphoproteins I. Phosphate cyc Journal of Virology 33, 167-182, 1980.
Richard A.F. Dixon and Priscilla A. Schaffer Fine-structure mapping and functional analysis of tem Journal of Virology 36, 189-203, 1980.
Lorna A. Samaniego, Arthus L. Webb and Neal A Deluca Functional interactions between herpes simplex virus Journal of Virology, 69, 5705-5715, 1995.
Rosario Leopardi and Bernard Roizman Functional interaction and colocalization of the herp Proceedings National Acadamy Science 93, 4572-76, 1996.
Stephen A Rice, Melissa C. Long, Vivian Lam, Priscill Herpes simplex virus immediate-early protein ICP22 is Journal of Virology, 69, 5550-59, 1995.
Alice M. McCarthy, Linda McMahan and Priscilla A Scha Herpes simplex virus type I Icp27 deletion nutants Journal of Virology, 63, 18-27, 1989.
Wendy R. Sacks, Constance C. Greene, Doris P. Aschman Herpes simplex virus type I ICP27 is an essential reg Journal of Virology 55, 796-805 1985.
Rolf Ingemarson , Hilkka Lankinen The herpes simplex virus type 1 robonucleotide reduct Virology, 156, 417-422, 1987.
C.C. Smith, M. Kulka, J.P. Wymer, T.D. Chung and L. A Expression of the large subunit of herpes simplex vir Journal General Virology, 73, 1417-1428, 1992.
Peir Franco Pignatti, Enzo Cassai, Guerrino Meneguzzi Herpes simplex virus DNA isolation from infected cell Virology 93, 260-264, 1979.
David J. Goldstein and Sandra K. Weller Factor(s) present in herpes simplex virus type 1-infe Virology 166, 41-51, 1988.
James P. Wymer, Theodore D. Chung, Yung-Nien Chang, Identification of immediate-early-type cis-response Journal of Virology 63, 2773-2784, 1989.
Theodore D. Chung, Jianhua Luo, James P. Wymer, Cynthi Leucine repeats in the large subunit of herpes simplex Journal of General Virology 72, 1139-1144, 1991.
Laure Aurelian 27 Herpes simplex viruses. 473-499, unnamed, undated.
L. Aurelian, P. Tarzano, C.C. Smith, T. Chung, A. Sham Amino-terminal epitope of herpes simplex virus type 2 Cancer cells 7 187-191, 1989.
Ann M. Arvin, Charles G. Prober Herpes simplex virus type 2--a persistent problem New England Journal Medicine, Oct. 16, 1997, 1158-9, v. 337.
Rhoda L. Ashley, Julie Dalessio, Sandra Burchett, Zane Herpes simplex virus-w (HSV) type-specific antibody co Journal Clinical Investigation, 90, 511-14, 1992.
Laure Aurelian Herpes simplex 73-100, unnamed, undated.
Douglas T. Fleming, Geraldine M. McQuillan, Robert E. Herpes simplex virus type 2 in the United States 1976 New England Journal of Medicine 337, 1105-1111, 1997.
Richard J. Whitley, John W. Gnann, Jr. Acyclovir: a decade later New England Journal of Medicine, 327, 782-789, 1992.
Laure Aurelian Preface, Herpesviruses, the immune system, and aids. xiii-xiv, 1990.
Robert P. Jacobs, Laure Aurelian, Gerald A Cole Cell-mediated immune response to herpes simplex virus: Journal of Immunology, 116, 1520-1525, 1976.
Laure Aurelian, Ivor Royston, Hugh J. Davis Antibody to genital herpes simplex virus: association Journal of National Cancer Institute, 45, 455-463, 1970.
John W. Nelson, Joa Zhu, Cynthia C. Smith, Michael Kul ATP and SH3 binding sites in the protein kinase of the Journal of Biological Chemistry, 271, 17021-27, 1996.
Theodore D. Chung, James P. Wymer, Michael Kulka, Cynt Myristylantion and polylysine-mediated activation of t Virology 179, 168-178, 1990.
C.C. Smith, J.H. Luo, J.C.R. Hunter, J.V. Ordonez and The transmembrane domain of the large subunit of HSV-2 Virology, 200, 598-612, 1994.
Laure Aurelian Herpes simplex virus type 2: unique biological propert Frontiers in Bioscience, 3, 1-15, 1998.
Jian-Hua Luo and Laure Aurelian The transmembrane helical segment but not the invarian Journal of Biological Chemictry, 267, 9645-53, 1992.
Jian-Hua Luo, Cynthia C. Smith, Michael Kulka, Laure A A truncated protein kinase domain of the large subunit Journal Biological Chemistry, 266, 20976-83, 1991.
J.C.R. Hunter, C.C. Smith, Debashish Bose, Michael Kul Intracellular internalization and signaling pathways Virology, 210, 345-360, 1995.
Raxit J. Jariwalla, Laure Aurelian, Paul O.P. Ts'o Tumorigenic transformation induced by a specific frag Proceedings National Acadamy Science 77,2279-83, 1980.
Theodore D. Chung, James P. Wymer, Cynthia C. Smith, Protein kinase activity associated with the large subu Journal of Virology 63, 3389-98, 1989.
Tao Peng, James R.C. Hunter, John W. Nelson The novel protein kinase of the RR1 subunit of herpes Virology, 216, 184-196, 1996.
J. Conner, J. Murray, A. Cross, J.B. Clements, and H.S Intracellular localisation of herpes simplex virus typ Virology, 213, 615-623, 1995.
J. Cooper, J. Conner, J.B. Clements Characterization of the novel protein kinase activity Journal of Virology, 69, 4979-85, 1995.
Ionnis Nikas, Nohn McLauchlan, Andrew J. Davison, Will Structural features of ribonucleotide reductase Proteins structure Function genetics 1,376-384, 1986.
Yoshinobu Hayashi, Tsuyoshi Iwasaka, Cynthia C. Smith Multistep transformation by defined fragments of herpe Proceedings National Acadmy Science 82, 8493-97, 1985.
Ramsey Williams S.
Scheiner Laurie
University of Maryland Baltimore
LandOfFree
Vaccine composition for herpes simplex virus and method of using does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Vaccine composition for herpes simplex virus and method of using, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vaccine composition for herpes simplex virus and method of using will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-991306