Vaccine composition comprising virus-like particles of human...

Details Vaccine composition comprising virus-like particles of human... Vaccine composition comprising virus-like particles of human...

2007-05-15

2007-05-15

Salimi, Ali R. (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

C424S202100, C435S006120, C435S069100

Reexamination Certificate

active

10508222

ABSTRACT:
The present invention relates to a vaccine composition comprising VLPs containing L1 proteins or functional L1 protein derivatives from HPV 16, HPV 18, HPV 31 and HPV 45 genotypes.

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Wheeler, “Preventive vaccines for cervical cancer”Salud Publica de Mexico39(4) pp. 283-287 (1997).
Giuliano et al. “Human papillomavirus infection at the United States-Mexico Border: Implications for cervical cancer prevention and control”Cancer Epidemiology Biomarkers&Prevention. 10(11) pp. 1129-1136 (2001).
Roden etal. “Assesment of serological relatedness of genital human papillomaviruses by hemagglutination inhibition”J of Virology, The American Society for Microbiology70(5) pp. 1996-2005 (1996).
Palker et al. “Antibody, cytokine and cytotoxic T lymphocyte responses in chimpanzees immunized with human papillomavirus virus-like particles”Vaccine, Butterworth Scientific19(27) pp. 3733-3743 (2001).

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