Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin
Reexamination Certificate
2011-08-30
2011-08-30
Seidel, Marianne C (Department: 1646)
Drug, bio-affecting and body treating compositions
Lymphokine
Interleukin
C530S351000
Reexamination Certificate
active
08007776
ABSTRACT:
Vaccine composition containing IL-15 for active immunization to treatment diseases related to over-expression of this cytokine. The technical aim pursued in this invention is to inhibit IL-15 activity through development of a therapeutic vaccine which elicits IL-15 neutralizing antibodies in the immunized host.IL-15 can be presented in this vaccine composition either alone or coupled to a carrier such as the P64k protein with a vaccine adjuvant such as Aluminum hydroxide.Besides, this invention is related to the use of this vaccine for treatment of Rheumatoid arthritis and other IL-15 over-expressing related diseases, and leukemia, where this cytokine acts as a growth factor.
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Diaz Yanelis Morera
Martinez Castillo Jose Rafael
Moro Soria Alejandro
Perea Rodriguez Silvio Ernesto
Perez Haydee Geronimo
Centro de Ingenieria Genetica y Biotecnologia
Hissong Bruce D
Hoffmann & Baron , LLP
Seidel Marianne C
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