Vaccine composition comprising autologous epidermal growth facto

Details Vaccine composition comprising autologous epidermal growth facto Vaccine composition comprising autologous epidermal growth facto

1996-02-21

1999-04-13

Minnifield, Nita

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

4241841, 4241981, 4241301, 4241581, 514 12, 530350, A61K 3900, A61K 39385, A61K 3940, A61K 39395

Patent

active

058940189

ABSTRACT:
The invention provides novel uses of EGF and vaccine compositions comprising EGF. In particular, autologous EGF, or a fragment or a derivative thereof, is used as an active immunization against the proliferation of EGF-dependent tumors, or other EGF-dependent diseases. Autologous EGF is preferably coupled to a carrier protein, such as tetanus toxoid or Cholera toxin B chain. The vaccine compositions according to the invention will usually comprise an adjuvant such as aluminum hydroxide.

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