Vaccine composition against Rhodococcus equi

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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C435S170000

Reexamination Certificate

active

08052978

ABSTRACT:
A method for preparing a soluble antigenic extract fromRhodococcus equiis disclosed. The method includes a step of solubilizing membranes of said bacteria by contacting said bacteria with an extraction solution containing a nonionic detergent of sorbitan polyethylene fatty acid ester type. Also disclosed is a soluble antigenic extract obtainable by said preparation method, said extract including membrane antigens ofRhodococcus equidissolved in the extraction solution. Finally, a composition including the soluble antigenic extract as a medicine is disclosed, including preferably a nanoparticulate or oil-in-water emulsion type adjuvant, and the use of the soluble antigenic extract for preparing a pharmaceutical composition for preventing or treating aRhodococcus equi-induced infection in an animal.

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