Vaccine and serum for endotoxin associated disease immunization

Details Vaccine and serum for endotoxin associated disease immunization Vaccine and serum for endotoxin associated disease immunization

1993-09-27

1997-06-24

Sidberry, Hazel F.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424 932, 4241841, 4241931, 4241971, 4242781, A61K 39112, A61K 3939, A61K 31715, A61K 4500

Patent

active

056414927

ABSTRACT:
A combination vaccine, with methods of preparation and treatment, for protection against Gram negative bacterial diseases. The vaccine includes a killed suspension of a bacterial mutant from the taxonomic family Enterobacteriaceae, a B-lymphocyte proliferating immune modulator, and a protein and lipid binding adjuvant. A hyperimmune serum for treating diseased animals is prepared by vaccinating a donor animal with the combination vaccine and then preparing clot serum containing antigen specific antibodies. The mutant is ATCC No. 53000 and is produced by ionizing radiation of Salmonella enteritidis. The immune modulator is a detoxified extract of lipopolysaccharide and is useful with many antigens to enhance primary immune response.

REFERENCES:
patent: 3075883 (1963-01-01), Schen et al.
patent: 4029762 (1977-06-01), Galanos et al.
patent: 4242270 (1980-12-01), Ayme et al.
patent: 4327082 (1982-04-01), Armitage
patent: 4328210 (1982-05-01), Kucera
patent: 4335107 (1982-06-01), Snoeyenbos et al.
patent: 4338298 (1982-07-01), Myers
patent: 4343792 (1982-08-01), Gouet et al.
patent: 4350684 (1982-09-01), Pardon et al.
patent: 4404186 (1983-09-01), Ron
Johns, Biol. Abs. 64: 50338, 1979.
McCabe, T. Inf. Dis., 136, 5161-6, (1977).
McCabe, Prog. Clin Biol, Res., 47; 107-17, (1980). (Medline Abstract #811 51080.
Hodgin et al, Infection, 4(2), 5-10, 1976 (Abstract Medline #770 7820.
Morrison et al, Adv. Immunol., vol. 28, pp. 294-450, (1979).
Smith et al. A Prelimary Evalution of Some Preparations of Styphimurium as Vaccines in Horses pp. 211-215 Date Approx. 1981.
Hodgin et al Infection 1976 4:5-10 Abstract.
Kinney et al J of Bact 95: 406-417 1968 Antibody Response & Protection Induced by Immunyote with Smooth & Rough Strains of Experiment Salmonella.
Davis et al Microbiology 3rd Ed 1980 pp. 436-437, 447-448.
Crosa et al J of Bact 155:307-325 1973.
Crosa et al Journal of Bacteriology 115:307-315 1973.
Galanos et al, International Review of Biochemistry Biochemistry of Lipids II vol. 14 only pp. 250, 251, 254,255,-259.
Sonnenwirth, in Microbiology 3rd Edition Chapter 31 page 647.
Collins et al Infect & Immunity 6:451-458 1971.
Crosa et al J. of Bact. 115:307-315, 1973.
Smith, Abs U of Georgia Sep. 29, 1982 pp. 211-215.
Myers, L.L., 1980, "Passive Protection of Calves Against Experimentally Induced and Naturally Occurring Enteric Colibacillosis." Am. J. Vet. Res. vol. 41 No. 12, pp. 1952-1956.
Morris, D.D., et al. "Proceedings of the Conference of Research Workers and Animal Diseases--64th Annual Meeting"Chicago, Ill. Nov. 1983, Abstract 190.
"Effects of Immunization on Cardiopulmonary Alterations of Gram-Negative Endotoxemia"--Journal of Applied Physiology: Respiration, Environment, Exercise Physiology 56(3): 582-589.
Immunization with Rough Mutants of Salmonella minnesota--Journal of Infectious Diseases 147(1): 57-67.
"A preliminary evaluation of some Salmonella typhimurium as vaccines in horses". The University of Georgia, Sep. 28, 1982, pp. 211-215.
Aromatic-dependent Salmonella typhimurium as Modified Live Vaccines for Calves Smith, et al. 1984--A.m. J. Vet. Res. V. 45 #1. page 59.
Peptides as Requirement for Immunotherapy of the Guinea Pig, Cancer Immunol. Immunother. 7: 43-58, 1979.
Vaccination of Cows with an Escherichia coli Bacterin for the Prevention of Naturally Occurring Diarrheal Disease in their Calves. Am J. Vet. Res. vol 37, No. 7, pp. 831-834.
Acres, et al. "Antigen-extinction profile in pregnant cows . . . ", Am. J. Vet. Res. vol. 43, No. 4, pp. 569-575.
Johnston, et al. "Resistance of Neonatal Calves Given Clostrum Diet . . . " Am. J. Vet. Res., vol 38, No. 9, pp. 1323-1326.
Ward, et al. "Use of a Formalin-Treated, Live Escherichia coli Vaccine . . . " JAVMA, vol. 168, No. 4, pp. 317-318.
Ziegler, et al. "Treatment of Gram-negative bacteremia and shock . . . " The New England Journal of Medicine 307(20): 1225-1230.
Prophylaxis and Therapy with Anti-Endotoxin . . . Proceedings of American Assoc. of Equine Practioners, 1982, Atlanta, Georgia.
"Thomson, et al. 1983 The use of Equine Anti-Endotoxin hyperimmune Serum . . . " Journal of the South African Veterinary Association 54:259-281.
Thomson, M., 1984--"Equine anti-endotoxin hyperimmune serium . . . "--Equine Practice-Medicine/Orthopedics 6(2):8-10.
Chemical Abstracts, vol 76, Abstract No. 31062, 1972.
Chemical Abstracts, vol 89, Abstract No. 19524p, 1978.
Biological Abstracts, vol 62, Abstract No. 37306, 1976.
Johns, et al., J. Infectious Diseases, vol. 147, pp. 57-67, 1983.
Kawakami et al., J. Bacteriology, vol. 92, pp. 1585-1589, 1966.
Biological Abstracts, vol. 70, Abstract No 44015, 1980.
Biological Abstracts, vol. 79, Abstract No. 13284, 1984.

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