Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1994-12-20
1998-08-04
Chambers, Jasemine C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
4241991, 424 931, 424 932, 4353201, 435325, C12N 1500
Patent
active
057893888
ABSTRACT:
The present invention relates to a vaccine against a virus associated with antibody-dependent-enhancement of viral infectivity. Such a vaccine comprises a herpesvirus vector which is able to spread from cell-to-cell and which does produce non-infectious progeny virions having a gene encoding an antigen of said virus inserted into the herpesvirus genome.
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W.E. Robinson et al., "Antibody-dependent enhancement of human immunodeficiency virus type 1 (HIV-1) infection in vitro by serum from HIV-1 infected and passively immunized chimpanzees," Proceedings of the National Academy of Science of US, 86:12, Jun. 1989 pp. Apr. 10-Apr. 14, Washington DC.
Mettenleiter Thomas Christoph
Van Woensel Petrus Alphonsus Maria
Visser Nicolaas
Akzo Nobel N.V.
Chambers Jasemine C.
Clark Deborah J. R.
Gormley Mary E.
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