Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1985-08-02
1987-08-11
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Lymphokine
530350, A61K 3900, C07K 1300
Patent
active
046861017
ABSTRACT:
A gene of varicella-zoster virus (VZV) which encodes immunogenic outer surface viral proteins has been identified by DNA sequence analysis. This gene can hybrid select messenger RNA which encodes and expresses a protein which reacts with human canvalescent zoster sera and with polyclonal monospecific antisera which neutralize viral infectivity. These proteins are useful for the preparation of a vaccine for VZV.
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Davison Andrew J.
Ellis Ronald W.
Keller Paul M.
Lowe Robert S.
Merck & Co. , Inc.
Perrella Donald J.
Pfeiffer Hesna J.
Phillips Delbert R.
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